Sys Stybe Johansen

Sys Stybe Johansen

Associate Professor


  1. 2024
  2. Accepted/In press

    Automated enzymatic hydrolysis of urine samples for improved systematic toxicological analysis of drug-facilitated sexual assault cases

    Skov, Kathrine Østerballe, Johansen, Sys Stybe, Linnet, Kristian & Nielsen, Marie Katrine Klose, 2024, (Accepted/In press) In: Drug Testing and Analysis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    CCH attack frequency reduction after psilocybin correlates with hypothalamic functional connectivity

    Madsen, M. K., Petersen, A. S., Stenbæk, Dea Siggaard, Sørensen, I. M., Schiønning, H., Fjeld, T., Nykjær, C. H., Larsen, S. M. U., Grzywacz, M., Mathiesen, T., Klausen, I. L., Overgaard-Hansen, O., Brendstrup-Brix, K., Linnet, Kristian, Johansen, Sys Stybe, Fisher, P. M., Jensen, Rigmor Højland & Knudsen, Gitte Moos, 2024, In: Headache. 64, 1, p. 55-67

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published
  5. 2023
  6. Published

    A Systematic Toxicological Analysis Strategy for Drug: Facilitated Sexual Assault Cases

    Skov, Kathrine Østerballe, Johansen, Sys Stybe, Linnet, Kristian & Nielsen, Marie Katrine Klose, May 2023, 7th Annual Meeting of the Nordic Association of Forensic Toxicologists (NAFT): Abstract book. Copenhagen: Nordic Association of Forensic Toxicologists (NAFT), 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

  7. Published

    Detection of scopolamine in urine and hair in a drug-facilitated sexual assault

    Melchior, S. E., Nielsen, Marie Katrine Klose, Oropeza, A. R., Banner, Jytte & Johansen, Sys Stybe, 2023, In: Forensic Science International. 347, 5 p., 111678.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Detection of scopolamine in urine and hair in a drug-facilitated sexual assault case

    Melchior, S. E., Nielsen, Marie Katrine Klose, Oropeza, A. R., Banner, Jytte & Johansen, Sys Stybe, 2023, TIAFT 2023: 60th International Association of Forensic Toxicologists Meeting: Abstract book. p. 108-108 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

  9. Published

    Detection of scopolamine in urine and hair in a drug-facilitated sexual assault case

    Melchior, S. E., Nielsen, Marie Katrine Klose, Oropeza, A. R., Banner, Jytte & Johansen, Sys Stybe, 2023, p. P51. 1 p.

    Research output: Contribution to conferencePosterResearch

  10. Published

    Driving under the Influence of Amphetamine: Analytical Evaluation of Illegal or Prescription Drug Intake Using Chiral UHPLC-MS/MS

    Nielsen, Marie Katrine Klose, Andersen, N. Z., Rasmussen, Brian Schou & Johansen, Sys Stybe, 2023, In: Journal of Analytical Toxicology. 47, 3, p. 280-286

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published
  12. Published

    Reference concentrations and distribution of 7-aminoclonazepam in hair following a single dose of clonazepam

    Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Kronstrand, R., 2023. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  13. Published

    Reference concentrations and distribution of 7-aminoclonazepam in hair following a single dose of clonazepam

    Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Kronstrand, R., 2023. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  14. Published

    Toxicological investigations in drug-facilitated sexual assault cases

    Skov, Kathrine Østerballe, Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Linnet, Kristian, 2023, Copenhagen: University of Copenhagen. 77 p.

    Research output: Book/ReportPh.D. thesisResearch

  15. Published
  16. Published
  17. Published

    What’s in the sample? Toxicological findings from drug-facilitated sexual assault cases in eastern Denmark from 2015–2022

    Skov, Kathrine Østerballe, Johansen, Sys Stybe, Linnet, Kristian & Nielsen, Marie Katrine Klose, 2023, 60th International Association of Forensic Toxicologists Meeting (TIAFT): Abstract book. Rome: TIAFT, p. 95-95

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

  18. 2022
  19. Published

    A review on the forensic toxicology of global drug-facilitated sexual assaults

    Skov, Kathrine Østerballe, Johansen, Sys Stybe, Linnet, Kristian & Nielsen, Marie Katrine Klose, 2022, In: European Review for Medical and Pharmacological Sciences. 26, 1, p. 183-197

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Concentrations of citalopram and escitalopram in postmortem hair segments

    Rygaard, K., Nielsen, Marie Katrine Klose, Linnet, Kristian, Banner, Jytte & Johansen, Sys Stybe, 2022, In: Forensic Science International. 336, 8 p., 111349.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Improving analysis of urine samples from drug-facilitated sexual assault cases

    Skov, Kathrine Østerballe, Johansen, Sys Stybe, Linnet, Kristian & Nielsen, Marie Katrine Klose, 2022, In: Toxicologie Analytique et Clinique. 34, 3 Suppl, p. S168-S169 P164.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    Postmortem hair, a tool for time resolved analysis of antipsychotics and antidepressants

    Svane, K. R. & Johansen, Sys Stybe, 2022, University of Copenhagen. 48 p.

    Research output: Book/ReportPh.D. thesisResearch

  23. Published

    Psilocybin-induced reduction in chronic cluster headache attack frequency correlates with changes in hypothalamic functional connectivity

    Madsen, M. K., Petersen, A. S., Stenbæk, Dea Siggaard, Sorensen, I. M., Schionning, H., Fjeld, T., Nykjaer, C., Larsen, S. M. U., Grzywacz, M., Mathiesen, T., Klausen, I., Hansen, O. O., Brendstrup-Brix, K., Linnet, Kristian, Johansen, Sys Stybe, Fisher, P. M., Jensen, Rasmus Herlo Beenfeldt, Knudsen, Gitte Moos & Madsen, M. K., 2022, medRxiv, 17 p.

    Research output: Working paperPreprintResearch

  24. 2021
  25. Published

    Hair cortisol concentrations in decedents with severe mental illness – An autopsy-based cohort study

    Busch, Johannes Rødbro, Wang, X., Lynnerup, Niels, Jacobsen, Christina, Jørgensen, Martin Balslev, Linnet, Kristian, Johansen, Sys Stybe & Banner, Jytte, Jul 2021, In: Forensic Science International: Reports. 3, 5 p., 100173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Postmortem Brain-Blood Ratios of Codeine, Fentanyl, Oxycodone and Tramadol

    Nedahl, Michael, Johansen, Sys Stybe & Linnet, Kristian, Jan 2021, In: Journal of Analytical Toxicology. 45, 1, p. 53–59 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A Systematic Review of Metabolite-to-Drug Ratios of Pharmaceuticals in Hair for Forensic Investigations

    Rygaard, K., Linnet, Kristian & Johansen, Sys Stybe, 2021, In: Metabolites. 11, 10, 28 p., 686.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Effects of a single dose of psilocybin on behaviour, brain 5-HT2A receptor occupancy and gene expression in the pig

    Donovan, L. L., Johansen, Jens Vilstrup, Ros, N. F., Jaberi, E., Linnet, Kristian, Johansen, Sys Stybe, Ozenne, Brice Maxime Hugues, Issazadeh-Navikas, Shohreh, Hansen, H. D. & Knudsen, Gitte Moos, 2021, In: European Neuropsychopharmacology. 42, p. 1-11

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Postmortem segmental hair analysis: analysing frequently used antipsychotics in long-term consumers

    Günther, K. N. & Johansen, Sys Stybe, 2021, In: TIAFT Bulletin. 51, 1, p. 19-26

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience

    Madsen, M. K., Stenbæk, Dea Siggaard, Arvidsson, A., Armand, Sophia, Marstrand-Joergensen, M. R., Johansen, Sys Stybe, Linnet, Kristian, Ozenne, Brice Maxime Hugues, Knudsen, Gitte Moos & Fisher, P. M., 2021, In: European Neuropsychopharmacology. 50, p. 121-132 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2020
  32. Published

    Concentrations of aripiprazole and dehydroaripiprazole in hair segments from deceased individuals with mental disorders

    Rygaard, K., Linnet, Kristian, Banner, Jytte & Johansen, Sys Stybe, Dec 2020, In: Forensic Science International. 317, 8 p., 110523.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Temporal patterns of tramadol in hair after a single dose

    Johansen, Sys Stybe, Dang, L. T. V. L., Nielsen, Marie Katrine Klose, Haage, P., Kugelberg, F. C. & Kronstrand, R., Nov 2020, In: Forensic Science International. 316, 9 p., 110546.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Segmental hair analysis of olanzapine and N-desmethyl-olanzapine in postmortem hair from mentally ill patients by LC–MS/MS

    Günther, K. N., Banner, Jytte, Linnet, Kristian & Johansen, Sys Stybe, 25 Oct 2020, In: Journal of Pharmaceutical and Biomedical Analysis. 190, 9 p., 113510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Internal quality control samples for hair testing

    Nielsen, Marie Katrine Klose & Johansen, Sys Stybe, 5 Sep 2020, In: Journal of Pharmaceutical and Biomedical Analysis. 188, 7 p., 113459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Ketamine analogues: Comparative toxicokinetic in vitro–in vivo extrapolation and quantification of 2-fluorodeschloroketamine in forensic blood and hair samples

    Davidsen, A. B., Mardal, Marie, Holm, N. B., Andreasen, A. K., Johansen, Sys Stybe, Noble, C., Dalsgaard, Petur Weihe & Linnet, Kristian, 20 Feb 2020, In: Journal of Pharmaceutical and Biomedical Analysis. 180, 113049.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Distribution of zopiclone and main metabolites in hair following a single dose

    Hansen, Stine Lund, Johansen, Sys Stybe, Nielsen, Marie Katrine Klose, Nilsson, G. & Kronstrand, R., Jan 2020, In: Forensic Science International. 306, 9 p., 110074.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    In vitro and in vivo metabolism and detection of 3-HO-PCP, a synthetic phencyclidine, in human samples and pooled human hepatocytes using high resolution mass spectrometry

    Davidsen, A. B., Mardal, Marie, Johansen, Sys Stybe, Dalsgaard, Petur Weihe & Linnet, Kristian, 2020, In: Drug Testing and Analysis. 12, 7, p. 987-993 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2019
  40. Published

    Hair testing for cortisol by UPLC-MS/MS in a family: External cross-contamination from use of cortisol cream

    Wang, X., Busch, Johannes Rødbro, Banner, Jytte, Linnet, Kristian & Johansen, Sys Stybe, Dec 2019, In: Forensic Science International. 305, 7 p., 109968.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Amitriptyline accumulation in tissues after coated activated charcoal hemoperfusion—a randomized controlled animal poisoning model

    Jansen, T., Hoegberg, L. C. G., Eriksen, Thomas, Dalhoff, Kim, Belhage, B. & Johansen, Sys Stybe, Oct 2019, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 392, 10, p. 1285–1292

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Brain-blood ratio of morphine in heroin and morphine autopsy cases

    Nedahl, Michael, Johansen, Sys Stybe & Linnet, Kristian, 1 Aug 2019, In: Forensic Science International. 301, p. 388-393

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published
  44. Published

    Postmortem Brain-Blood Ratios of Amphetamine, Cocaine, Ephedrine, MDMA and Methylphenidate

    Nedahl, Michael, Johansen, Sys Stybe & Linnet, Kristian, Jun 2019, In: Journal of Analytical Toxicology. 43, 5, p. 378–384

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Clinical signs in a non-Parkinson’s patient from therapeutic doses of pramipexol given in error – and antidotal reversal

    Bøgevig, S., Johansen, Sys Stybe, Kruse, H. & Heogberg, L., 24 May 2019, In: Clinical Toxicology. 57, 6, p. 511 1 p., 190.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Published
  47. Published

    Segmental Hair Analysis-Interpretation of the Time of Drug Intake in Two Patients Undergoing Drug Treatment

    Wang, X., Johansen, Sys Stybe, Nielsen, Marie Katrine Klose & Linnet, Kristian, May 2019, In: Journal of Forensic Sciences. 64, 3, p. 950-955

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Prolonged clinical course from suspected verapamil bezoar formation in an intentional massive overdose from verapamil and enalapril.

    Hoegsberg, L., Johansen, Sys Stybe, Petersen, T., Palmqvist, D. & Boegevig, S., 2019, In: Clinical Toxicology. 57, 6, p. 515 1 p., 198.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. Published

    Psilocybin occupancy of brain serotonin 2A receptors correlates with psilocin levels and subjective experience: a [11C]Cimbi-36 PET study in humans

    Madsen, M. K., Burmester, D., Stenbaek, D. S., Kristiansen, S., Dyssegaard, A., Lehel, S., Linnet, Kristian, Johansen, Sys Stybe, Svarer, C., Ozenne, B., Erritzoe, D., Fisher, P. M. & Knudsen, Gitte Moos, 2019, In: European Neuropsychopharmacology. 29, Suppl. 1, p. S304-S305

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Published

    Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels

    Madsen, M. K., Fisher, P. M., Burmester, D., Dyssegaard, A., Stenbæk, D. S., Kristiansen, S., Johansen, Sys Stybe, Lehel, S., Linnet, Kristian, Svarer, C., Erritzoe, D., Ozenne, Brice Maxime Hugues & Knudsen, Gitte Moos, 2019, In: Neuropsychopharmacology. 44, p. 1328-1334

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2018
  52. Published

    Fatal intoxications among non-drug addicts in Eastern Denmark over a 5-year period (2008–2012)

    Johansen, Sys Stybe, Jacobsen, Christina & Linnet, Kristian, 4 Dec 2018, In: Research and Reports in Forensic Medical Science. 8, p. 9—16

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Reference Brain and Blood Concentrations of Olanzapine in Postmortem Cases

    Nedahl, Michael, Johansen, Sys Stybe & Linnet, Kristian, 1 Nov 2018, In: Journal of Analytical Toxicology. 42, 9, p. 650-654 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Segmental Analysis of Chlorprothixene and Desmethylchlorprothixene in Postmortem Hair

    Günther, K. N., Johansen, Sys Stybe, Wicktor, P., Banner, Jytte & Linnet, Kristian, 1 Nov 2018, In: Journal of Analytical Toxicology. 42, 9, p. 642-649

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Postmortem analysis of three methoxyacetylfentanyl-related deaths in Denmark and in vitro metabolite profiling in pooled human hepatocytes

    Mardal, Marie, Johansen, Sys Stybe, Davidsen, A. B., Telving, R., Jornil, J. R., Dalsgaard, Petur Weihe, Hasselstrøm, J. B., Øiestad, Å. M., Linnet, Kristian & Andreasen, M. F., Sep 2018, In: Forensic Science International. 290, p. 310-317

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Metabolite Profiling of Methoxyacetylfentanyl in Pooled Human Hepatocytes and Quantitation in Biological Samples from a Postmortem Forensic Case

    Mardal, Marie, Johansen, Sys Stybe, Davidsen, A. B., Dalsgaard, Petur Weihe & Linnet, Kristian, 28 Aug 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  57. Published
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