A report of the 2002-2008 paternity testing workshops of the English speaking working group of the International Society for Forensic Genetics
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A report of the 2002-2008 paternity testing workshops of the English speaking working group of the International Society for Forensic Genetics. / Thomsen, Anni Rønfeldt; Hallenberg, Charlotte; Simonsen, Bo Thisted; Langkjaer, Rikke Breinhold; Morling, Niels.
I: Forensic Science International: Genetics, Bind 3, Nr. 4, 2009, s. 214-21.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - A report of the 2002-2008 paternity testing workshops of the English speaking working group of the International Society for Forensic Genetics
AU - Thomsen, Anni Rønfeldt
AU - Hallenberg, Charlotte
AU - Simonsen, Bo Thisted
AU - Langkjaer, Rikke Breinhold
AU - Morling, Niels
PY - 2009
Y1 - 2009
N2 - The English Speaking Working Group (ESWG) of the International Society for Forensic Genetics (ISFG) offers an annual Paternity Testing Workshop open to all members of the group. Blood samples, a questionnaire and a paper challenge are sent to the participants. Here, we present the results of the 2002-2008 Paternity Testing Workshops with the objective to evaluate the uniformity of DNA-profiling and conclusions of the participating laboratories as well as to clarify tendencies in typing strategies and biostatistical evaluations of the laboratories. The numbers of participating laboratories increased from 46 in 2002 to 68 in 2008. The results showed an increasing degree of concordance concerning methods and DNA systems used and a high degree of uniformity in typing results with discrepancies in 0.1 and 0.3 % of all submitted PCR-based results. The paper challenges showed uniformity in the calculation of the weight of evidence for simple cases with straight-forward genetic constellations. However, a high degree of variation existed in complex scenarios with rare genetic constellations such as genetic inconsistencies/possible silent alleles, rare alleles and haplotypes.
AB - The English Speaking Working Group (ESWG) of the International Society for Forensic Genetics (ISFG) offers an annual Paternity Testing Workshop open to all members of the group. Blood samples, a questionnaire and a paper challenge are sent to the participants. Here, we present the results of the 2002-2008 Paternity Testing Workshops with the objective to evaluate the uniformity of DNA-profiling and conclusions of the participating laboratories as well as to clarify tendencies in typing strategies and biostatistical evaluations of the laboratories. The numbers of participating laboratories increased from 46 in 2002 to 68 in 2008. The results showed an increasing degree of concordance concerning methods and DNA systems used and a high degree of uniformity in typing results with discrepancies in 0.1 and 0.3 % of all submitted PCR-based results. The paper challenges showed uniformity in the calculation of the weight of evidence for simple cases with straight-forward genetic constellations. However, a high degree of variation existed in complex scenarios with rare genetic constellations such as genetic inconsistencies/possible silent alleles, rare alleles and haplotypes.
U2 - 10.1016/j.fsigen.2009.01.016
DO - 10.1016/j.fsigen.2009.01.016
M3 - Journal article
C2 - 19647705
VL - 3
SP - 214
EP - 221
JO - Forensic Science International: Genetics
JF - Forensic Science International: Genetics
SN - 1872-4973
IS - 4
ER -
ID: 13834647