Concordance study and population frequencies for 16 autosomal STRs analyzed with PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ in Somalis, Danes and Greenlanders

Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt

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Concordance study and population frequencies for 16 autosomal STRs analyzed with PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ in Somalis, Danes and Greenlanders. / Tomas Mas, Carmen; Mogensen, H S; Friis, S L; Hallenberg, C; Stene, M C; Morling, N.

I: Forensic science international. Genetics, Bind 11, 06.2014, s. e18–e21.

Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt

Harvard

Tomas Mas, C, Mogensen, HS, Friis, SL, Hallenberg, C, Stene, MC & Morling, N 2014, 'Concordance study and population frequencies for 16 autosomal STRs analyzed with PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ in Somalis, Danes and Greenlanders', Forensic science international. Genetics, bind 11, s. e18–e21. https://doi.org/10.1016/j.fsigen.2014.04.004

APA

Tomas Mas, C., Mogensen, H. S., Friis, S. L., Hallenberg, C., Stene, M. C., & Morling, N. (2014). Concordance study and population frequencies for 16 autosomal STRs analyzed with PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ in Somalis, Danes and Greenlanders. Forensic science international. Genetics, 11, e18–e21. https://doi.org/10.1016/j.fsigen.2014.04.004

Vancouver

Tomas Mas C, Mogensen HS, Friis SL, Hallenberg C, Stene MC, Morling N. Concordance study and population frequencies for 16 autosomal STRs analyzed with PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ in Somalis, Danes and Greenlanders. Forensic science international. Genetics. 2014 jun.;11:e18–e21. https://doi.org/10.1016/j.fsigen.2014.04.004

Author

Tomas Mas, Carmen ; Mogensen, H S ; Friis, S L ; Hallenberg, C ; Stene, M C ; Morling, N. / Concordance study and population frequencies for 16 autosomal STRs analyzed with PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ in Somalis, Danes and Greenlanders. I: Forensic science international. Genetics. 2014 ; Bind 11. s. e18–e21.

Bibtex

@article{dbffb880aeb941c2af1657d0edd5b2dc,
title = "Concordance study and population frequencies for 16 autosomal STRs analyzed with PowerPlex({\textregistered}) ESI 17 and AmpFℓSTR({\textregistered}) NGM SElect{\texttrademark} in Somalis, Danes and Greenlanders",
abstract = "A concordance study of the results of PowerPlex({\textregistered}) ESI 17 and AmpFℓSTR({\textregistered}) NGM SElect{\texttrademark} kits obtained from 591 individuals from Somalia (N=198), Denmark (N=199) and Greenland (N=194) was performed. Among 9456 STR types, seven discordant results were found with the two kits: one observed in the D19S433 system in an individual from Denmark and six in the SE33 system in six individuals from Somalia. Sequencing of SE33 in the six samples with discordant results showed G>A transition 15bp downstream of the repeat unit in three of the individuals, and G>A transition 68bp downstream of the repeat unit in the other three individuals. Population data for 16 autosomal STR systems analyzed in 989 individuals from Somalia, Denmark and Greenland are also presented. The highest mean heterozygosity was observed in Danes (82.5%). With the exception of D8S1179 in Danes, no significant deviations from Hardy-Weinberg expectations were observed. Only one pair of systems (D12S391 and D18S51) showed significant allelic association in Greenlanders (after Holm-{\v S}id{\'a}k correction). A MDS plot drawn from pairwise FST values calculated between 21 populations showed a clear displacement of the Greenlandic population versus the other ones included in the analyses. The highest combined chance of exclusion and power of discrimination was observed for Danes reaching values of 99.9999987% and 1 in 1.8×10(21), respectively.",
author = "{Tomas Mas}, Carmen and Mogensen, {H S} and Friis, {S L} and C Hallenberg and Stene, {M C} and N Morling",
note = "Copyright {\textcopyright} 2014 Elsevier Ireland Ltd. All rights reserved.",
year = "2014",
month = jun,
doi = "10.1016/j.fsigen.2014.04.004",
language = "English",
volume = "11",
pages = "e18–e21",
journal = "Forensic Science International: Genetics",
issn = "1872-4973",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Concordance study and population frequencies for 16 autosomal STRs analyzed with PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ in Somalis, Danes and Greenlanders

AU - Tomas Mas, Carmen

AU - Mogensen, H S

AU - Friis, S L

AU - Hallenberg, C

AU - Stene, M C

AU - Morling, N

N1 - Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

PY - 2014/6

Y1 - 2014/6

N2 - A concordance study of the results of PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ kits obtained from 591 individuals from Somalia (N=198), Denmark (N=199) and Greenland (N=194) was performed. Among 9456 STR types, seven discordant results were found with the two kits: one observed in the D19S433 system in an individual from Denmark and six in the SE33 system in six individuals from Somalia. Sequencing of SE33 in the six samples with discordant results showed G>A transition 15bp downstream of the repeat unit in three of the individuals, and G>A transition 68bp downstream of the repeat unit in the other three individuals. Population data for 16 autosomal STR systems analyzed in 989 individuals from Somalia, Denmark and Greenland are also presented. The highest mean heterozygosity was observed in Danes (82.5%). With the exception of D8S1179 in Danes, no significant deviations from Hardy-Weinberg expectations were observed. Only one pair of systems (D12S391 and D18S51) showed significant allelic association in Greenlanders (after Holm-Šidák correction). A MDS plot drawn from pairwise FST values calculated between 21 populations showed a clear displacement of the Greenlandic population versus the other ones included in the analyses. The highest combined chance of exclusion and power of discrimination was observed for Danes reaching values of 99.9999987% and 1 in 1.8×10(21), respectively.

AB - A concordance study of the results of PowerPlex(®) ESI 17 and AmpFℓSTR(®) NGM SElect™ kits obtained from 591 individuals from Somalia (N=198), Denmark (N=199) and Greenland (N=194) was performed. Among 9456 STR types, seven discordant results were found with the two kits: one observed in the D19S433 system in an individual from Denmark and six in the SE33 system in six individuals from Somalia. Sequencing of SE33 in the six samples with discordant results showed G>A transition 15bp downstream of the repeat unit in three of the individuals, and G>A transition 68bp downstream of the repeat unit in the other three individuals. Population data for 16 autosomal STR systems analyzed in 989 individuals from Somalia, Denmark and Greenland are also presented. The highest mean heterozygosity was observed in Danes (82.5%). With the exception of D8S1179 in Danes, no significant deviations from Hardy-Weinberg expectations were observed. Only one pair of systems (D12S391 and D18S51) showed significant allelic association in Greenlanders (after Holm-Šidák correction). A MDS plot drawn from pairwise FST values calculated between 21 populations showed a clear displacement of the Greenlandic population versus the other ones included in the analyses. The highest combined chance of exclusion and power of discrimination was observed for Danes reaching values of 99.9999987% and 1 in 1.8×10(21), respectively.

U2 - 10.1016/j.fsigen.2014.04.004

DO - 10.1016/j.fsigen.2014.04.004

M3 - Letter

C2 - 24810256

VL - 11

SP - e18–e21

JO - Forensic Science International: Genetics

JF - Forensic Science International: Genetics

SN - 1872-4973

ER -

ID: 110458585