Review of the Forensic Applicability of Biostatistical Methods for Inferring Ancestry from Autosomal Genetic Markers

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The inference of ancestry has become a part of the services many forensic genetic laboratories provide. Interest in ancestry may be to provide investigative leads or identify the region of origin in cases of unidentified missing persons. There exist many biostatistical methods developed for the study of population structure in the area of population genetics. However, the challenges and questions are slightly different in the context of forensic genetics, where the origin of a specific sample is of interest compared to the understanding of population histories and genealogies. In this paper, the methodologies for modelling population admixture and inferring ancestral populations are reviewed with a focus on their strengths and weaknesses in relation to ancestry inference in the forensic context.

Original languageEnglish
Article number141
JournalGenes
Volume13
Issue number1
Number of pages11
ISSN2073-4425
DOIs
Publication statusPublished - 2022

    Research areas

  • ancestry, biostatistics, classification, clustering, distance based, hypothesis tests, likehood

ID: 291672199