A collaborative study of the EDNAP group regarding Y-chromosome binary polymorphism analysis
Research output: Contribution to journal › Journal article › Research › peer-review
A collaborative study was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the performance of Y-chromosome binary polymorphism analysis in different European laboratories. Four blood samples were sent to the laboratories, to be analysed for 11 Y-chromosome single nucleotide polymorphisms (SNPs): SRY-1532, M40, M35, M213, M9, 92R7, M17, P25, M18, M153 and M167. All the labs were also asked to submit a population study including these markers. All participating laboratories reported the same results, indicating the reproducibility and robustness of Y-chromosome SNP typing. A total of 535 samples from six different European populations were also analysed. In Galicia (NW Spain) and Belgium, the most frequent haplogroup was R1b*(xR1b1,R1b3df). Haplogroup F*(xK) is one of the most frequent in Austria and Denmark, while the lowest frequency appear in Belgium. Haplogroup frequencies found in this collaborative study were compared with previously published European Y-chromosome haplogroup data.
Original language | English |
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Journal | Forensic Science International |
Volume | 153 |
Issue number | 2-3 |
Pages (from-to) | 103-8 |
Number of pages | 5 |
ISSN | 0379-0738 |
DOIs | |
Publication status | Published - 2005 |
Bibliographical note
Keywords: Chromosomes, Human, Y; DNA Fingerprinting; Europe; Genetic Markers; Genetics, Population; Haplotypes; Humans; Male; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Reproducibility of Results
ID: 14145136