Comparison study of two different procedures for the determination of drugs of abuse in postmortem brain samples
Research output: Contribution to journal › Journal article › Research
The aim of this study was to compare two routine solid phase extraction methods for the analysis of body-fluids and tissue samples; a routine method developed in Vienna for tissue samples compared to a routine method developed in Copenhagen for blood. Our approach was to simply exchange the matrix from blood to brain and thereby see if we could avoid a time comsuming optimization of the Copenhagen method to accommodate the more complex brain matrix. Comparative analyses and quantification of eight drugs of abuse (methadone, morphine, amphetamine, benzoylecgonine, cocaine, morphine, codeine, diazepam and 7-aminoflunitrazepam) in 19 brain homogenates of authentic cases were conducted.
Original language | English |
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Journal | TIAFT Bulletin |
Volume | 44 |
Issue number | 1 |
Pages (from-to) | 26-30 |
Number of pages | 5 |
ISSN | 1080-9945 |
Publication status | Published - May 2014 |
ID: 130243109