Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases. / Vyberg, Mogens; Hougen, H P; Tønnesen.

In: Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, Vol. 91, No. 6, 11.1983, p. 483-7.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Vyberg, M, Hougen, HP & Tønnesen 1983, 'Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases', Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, vol. 91, no. 6, pp. 483-7.

APA

Vyberg, M., Hougen, H. P., & Tønnesen (1983). Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases. Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, 91(6), 483-7.

Vancouver

Vyberg M, Hougen HP, Tønnesen. Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases. Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology. 1983 Nov;91(6):483-7.

Author

Vyberg, Mogens ; Hougen, H P ; Tønnesen. / Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases. In: Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology. 1983 ; Vol. 91, No. 6. pp. 483-7.

Bibtex

@article{4f96008019524b5b9f1ac9fa078d45d1,
title = "Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases",
abstract = "101 gastrobioptic series from 93 consecutive patients with a final diagnosis of carcinoma of the stomach were reviewed. 20 false negative cases were found. Of these, ten cases were missed because of erroneous histopathological interpretation, two because of too few sections, and eight because carcinoma was not represented in the biopsies. The frequency of false negatives was slightly larger in ulcerating carcinomas than in polypoid and diffusely spreading carcinomas, mainly due to seven cases of ulcerating carcinoma being missed by the pathologist. There was no correlation between false negatives and histological type. The rate of false negatives was significantly higher in cases, where the number of biopsies taken was below seven. The rate of histopathological misinterpretations was significantly higher in cases, where the number of actually positive biopsies was below four. Attempts to increase the positive yield should be based on not only an evaluation of the biopsy technique, but also an analysis of the histopathological method and interpretation.",
keywords = "Biopsy, False Negative Reactions, Gastroscopy, Humans, Stomach, Stomach Neoplasms",
author = "Mogens Vyberg and Hougen, {H P} and T{\o}nnesen",
year = "1983",
month = nov,
language = "English",
volume = "91",
pages = "483--7",
journal = "Acta Pathologica Microbiologica et Immunologica Scandinavica - Section A Pathology",
issn = "0108-0164",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases

AU - Vyberg, Mogens

AU - Hougen, H P

AU - Tønnesen, null

PY - 1983/11

Y1 - 1983/11

N2 - 101 gastrobioptic series from 93 consecutive patients with a final diagnosis of carcinoma of the stomach were reviewed. 20 false negative cases were found. Of these, ten cases were missed because of erroneous histopathological interpretation, two because of too few sections, and eight because carcinoma was not represented in the biopsies. The frequency of false negatives was slightly larger in ulcerating carcinomas than in polypoid and diffusely spreading carcinomas, mainly due to seven cases of ulcerating carcinoma being missed by the pathologist. There was no correlation between false negatives and histological type. The rate of false negatives was significantly higher in cases, where the number of biopsies taken was below seven. The rate of histopathological misinterpretations was significantly higher in cases, where the number of actually positive biopsies was below four. Attempts to increase the positive yield should be based on not only an evaluation of the biopsy technique, but also an analysis of the histopathological method and interpretation.

AB - 101 gastrobioptic series from 93 consecutive patients with a final diagnosis of carcinoma of the stomach were reviewed. 20 false negative cases were found. Of these, ten cases were missed because of erroneous histopathological interpretation, two because of too few sections, and eight because carcinoma was not represented in the biopsies. The frequency of false negatives was slightly larger in ulcerating carcinomas than in polypoid and diffusely spreading carcinomas, mainly due to seven cases of ulcerating carcinoma being missed by the pathologist. There was no correlation between false negatives and histological type. The rate of false negatives was significantly higher in cases, where the number of biopsies taken was below seven. The rate of histopathological misinterpretations was significantly higher in cases, where the number of actually positive biopsies was below four. Attempts to increase the positive yield should be based on not only an evaluation of the biopsy technique, but also an analysis of the histopathological method and interpretation.

KW - Biopsy

KW - False Negative Reactions

KW - Gastroscopy

KW - Humans

KW - Stomach

KW - Stomach Neoplasms

M3 - Journal article

C2 - 6666585

VL - 91

SP - 483

EP - 487

JO - Acta Pathologica Microbiologica et Immunologica Scandinavica - Section A Pathology

JF - Acta Pathologica Microbiologica et Immunologica Scandinavica - Section A Pathology

SN - 0108-0164

IS - 6

ER -

ID: 44517208