Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases. / Vyberg, Mogens; Hougen, H P; Tønnesen.
In: Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, Vol. 91, No. 6, 11.1983, p. 483-7.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Diagnostic accuracy of endoscopic gastrobiopsy in carcinoma of the stomach. A histopathological review of 101 cases
AU - Vyberg, Mogens
AU - Hougen, H P
AU - Tønnesen, null
PY - 1983/11
Y1 - 1983/11
N2 - 101 gastrobioptic series from 93 consecutive patients with a final diagnosis of carcinoma of the stomach were reviewed. 20 false negative cases were found. Of these, ten cases were missed because of erroneous histopathological interpretation, two because of too few sections, and eight because carcinoma was not represented in the biopsies. The frequency of false negatives was slightly larger in ulcerating carcinomas than in polypoid and diffusely spreading carcinomas, mainly due to seven cases of ulcerating carcinoma being missed by the pathologist. There was no correlation between false negatives and histological type. The rate of false negatives was significantly higher in cases, where the number of biopsies taken was below seven. The rate of histopathological misinterpretations was significantly higher in cases, where the number of actually positive biopsies was below four. Attempts to increase the positive yield should be based on not only an evaluation of the biopsy technique, but also an analysis of the histopathological method and interpretation.
AB - 101 gastrobioptic series from 93 consecutive patients with a final diagnosis of carcinoma of the stomach were reviewed. 20 false negative cases were found. Of these, ten cases were missed because of erroneous histopathological interpretation, two because of too few sections, and eight because carcinoma was not represented in the biopsies. The frequency of false negatives was slightly larger in ulcerating carcinomas than in polypoid and diffusely spreading carcinomas, mainly due to seven cases of ulcerating carcinoma being missed by the pathologist. There was no correlation between false negatives and histological type. The rate of false negatives was significantly higher in cases, where the number of biopsies taken was below seven. The rate of histopathological misinterpretations was significantly higher in cases, where the number of actually positive biopsies was below four. Attempts to increase the positive yield should be based on not only an evaluation of the biopsy technique, but also an analysis of the histopathological method and interpretation.
KW - Biopsy
KW - False Negative Reactions
KW - Gastroscopy
KW - Humans
KW - Stomach
KW - Stomach Neoplasms
M3 - Journal article
C2 - 6666585
VL - 91
SP - 483
EP - 487
JO - Acta Pathologica Microbiologica et Immunologica Scandinavica - Section A Pathology
JF - Acta Pathologica Microbiologica et Immunologica Scandinavica - Section A Pathology
SN - 0108-0164
IS - 6
ER -
ID: 44517208