Effects of homozygosity of the nude (rnu) gene in an inbred strain of rats: studies of lymphoid and non--lymphoid organs in different age groups of nude rats of LEW background at a stage in the gene transfer

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Effects of homozygosity of the nude (rnu) gene in an inbred strain of rats : studies of lymphoid and non--lymphoid organs in different age groups of nude rats of LEW background at a stage in the gene transfer. / Hougen, H P; Klausen, B.

In: Laboratory Animals, Vol. 18, No. 1, 01.1984, p. 7-14.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hougen, HP & Klausen, B 1984, 'Effects of homozygosity of the nude (rnu) gene in an inbred strain of rats: studies of lymphoid and non--lymphoid organs in different age groups of nude rats of LEW background at a stage in the gene transfer', Laboratory Animals, vol. 18, no. 1, pp. 7-14.

APA

Hougen, H. P., & Klausen, B. (1984). Effects of homozygosity of the nude (rnu) gene in an inbred strain of rats: studies of lymphoid and non--lymphoid organs in different age groups of nude rats of LEW background at a stage in the gene transfer. Laboratory Animals, 18(1), 7-14.

Vancouver

Hougen HP, Klausen B. Effects of homozygosity of the nude (rnu) gene in an inbred strain of rats: studies of lymphoid and non--lymphoid organs in different age groups of nude rats of LEW background at a stage in the gene transfer. Laboratory Animals. 1984 Jan;18(1):7-14.

Author

Hougen, H P ; Klausen, B. / Effects of homozygosity of the nude (rnu) gene in an inbred strain of rats : studies of lymphoid and non--lymphoid organs in different age groups of nude rats of LEW background at a stage in the gene transfer. In: Laboratory Animals. 1984 ; Vol. 18, No. 1. pp. 7-14.

Bibtex

@article{9b70d6018e9f4382b95c2371c1b45a8a,
title = "Effects of homozygosity of the nude (rnu) gene in an inbred strain of rats: studies of lymphoid and non--lymphoid organs in different age groups of nude rats of LEW background at a stage in the gene transfer",
abstract = "Several age groups of nude homozygous rnu/rnu and heterozygous rnu/+ rats of the same genetic background at an early stage of back-crossing (LEW/Mol) were compared as to body and organ weights, histological appearance and cell density of lymphoid organs, haematological values and differential counts of bone marrow and peripheral blood. No thymic tissue was found in the nude animals. 7-week-old nudes were smaller than control animals and had relatively larger non-lymphoid organs and cell-depleted peripheral lymphoid organs. Other age groups showed little difference. Peripheral blood of nude rats showed no signs of lymphopaenia in contrast with the findings in nude mice. The number of thoracic duct lymphocytes was, however, significantly smaller in all age groups of the nude rats, and the bone marrow tended to contain fewer lymphocytes.",
keywords = "Age Factors, Animals, Bone Marrow Cells, Female, Heterozygote, Homozygote, Leukocyte Count, Lymphoid Tissue, Male, Organ Size, Rats, Rats, Inbred Lew, Rats, Nude",
author = "Hougen, {H P} and B Klausen",
year = "1984",
month = jan,
language = "English",
volume = "18",
pages = "7--14",
journal = "Laboratory Animals",
issn = "0023-6772",
publisher = "SAGE Publications",
number = "1",

}

RIS

TY - JOUR

T1 - Effects of homozygosity of the nude (rnu) gene in an inbred strain of rats

T2 - studies of lymphoid and non--lymphoid organs in different age groups of nude rats of LEW background at a stage in the gene transfer

AU - Hougen, H P

AU - Klausen, B

PY - 1984/1

Y1 - 1984/1

N2 - Several age groups of nude homozygous rnu/rnu and heterozygous rnu/+ rats of the same genetic background at an early stage of back-crossing (LEW/Mol) were compared as to body and organ weights, histological appearance and cell density of lymphoid organs, haematological values and differential counts of bone marrow and peripheral blood. No thymic tissue was found in the nude animals. 7-week-old nudes were smaller than control animals and had relatively larger non-lymphoid organs and cell-depleted peripheral lymphoid organs. Other age groups showed little difference. Peripheral blood of nude rats showed no signs of lymphopaenia in contrast with the findings in nude mice. The number of thoracic duct lymphocytes was, however, significantly smaller in all age groups of the nude rats, and the bone marrow tended to contain fewer lymphocytes.

AB - Several age groups of nude homozygous rnu/rnu and heterozygous rnu/+ rats of the same genetic background at an early stage of back-crossing (LEW/Mol) were compared as to body and organ weights, histological appearance and cell density of lymphoid organs, haematological values and differential counts of bone marrow and peripheral blood. No thymic tissue was found in the nude animals. 7-week-old nudes were smaller than control animals and had relatively larger non-lymphoid organs and cell-depleted peripheral lymphoid organs. Other age groups showed little difference. Peripheral blood of nude rats showed no signs of lymphopaenia in contrast with the findings in nude mice. The number of thoracic duct lymphocytes was, however, significantly smaller in all age groups of the nude rats, and the bone marrow tended to contain fewer lymphocytes.

KW - Age Factors

KW - Animals

KW - Bone Marrow Cells

KW - Female

KW - Heterozygote

KW - Homozygote

KW - Leukocyte Count

KW - Lymphoid Tissue

KW - Male

KW - Organ Size

KW - Rats

KW - Rats, Inbred Lew

KW - Rats, Nude

M3 - Journal article

C2 - 10628778

VL - 18

SP - 7

EP - 14

JO - Laboratory Animals

JF - Laboratory Animals

SN - 0023-6772

IS - 1

ER -

ID: 44521931