Fasting and postprandial serum concentrations of glycine- and taurine-conjugated bile acids in crohn's disease
Research output: Contribution to journal › Journal article › Research › peer-review
Fasting and postprandial serum concentrations of glycine and taurine conjugates of cholic, chenodeoxycholic, and deoxycholic acid were measured with a high-pressure liquid chromatographic-enzymatic assay in 17 patients with ileal Crohn's disease and in 17 controls. The postprandial concentrations of the taurine-conjugated bile acids in the patients were significantly lower than in the controls, whereas the concentrations of the glycine conjugates were not significantly different. The total glycine to taurine ratios of serum bile acids were significantly higher in the patients (means, 2.9 fasting and 4.8 postprandial) than in the controls (1.9 and 2.6). Of the patients, 65% had a postprandial total G/T ratio of serum bile acids which was above the control interval.
Original language | English |
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Book series | Scandinavian Journal of Gastroenterology |
Volume | 18 |
Issue number | 3 |
Pages (from-to) | 433-438 |
Number of pages | 6 |
ISSN | 0036-5521 |
DOIs | |
Publication status | Published - 1 Jan 1983 |
- Crohn's disease, Glycine- and taurine-conjugated bile acids, serum
Research areas
ID: 230032268