Latent Causes of Sudden Cardiac Arrest
Research output: Contribution to journal › Review › Research › peer-review
Inherited arrhythmia syndromes are a common cause of apparently unexplained cardiac arrest or sudden cardiac death. These include long QT syndrome and Brugada syndrome, with a well-recognized phenotype in most patients with sufficiently severe disease to lead to cardiac arrest. Less common and typically less apparent conditions that may not be readily evident include catecholaminergic polymorphic ventricular tachycardia, short QT syndrome and early repolarization syndrome. In cardiac arrest patients whose extensive testing does not reveal an underlying etiology, a diagnosis of idiopathic ventricular fibrillation or short-coupled ventricular fibrillation is assigned. This review summarizes our current understanding of the less common inherited arrhythmia syndromes and provides clinicians with a practical approach to diagnosis and management.
| Original language | English |
|---|---|
| Journal | JACC: Clinical Electrophysiology |
| Volume | 8 |
| Issue number | 6 |
| Pages (from-to) | 806-821 |
| ISSN | 2405-500X |
| DOIs | |
| Publication status | Published - Jun 2022 |
Bibliographical note
Funding Information:
The study was supported by the Heart in Rhythm Organization (Dr Krahn, principal investigator) that receives support from the Canadian Institute of Health Research (RN380020–406814). Dr Krahn receives support from the Sauder Family and Heart and Stroke Foundation Chair in Cardiology (Vancouver, BC), the Paul Brunes Chair in Heart Rhythm Disorders (Vancouver, BC), and the Paul Albrechtson Foundation (Winnipeg, MB). Dr Tfelt-Hansen has received support from the John and Birthe Meyer Foundation. Dr Tadros has received support from the Canadian Research Chair program. Dr Semsarian is the recipient of National Health and Medical Research Council (NHMRC) Practitioner Fellowship #1154992. Dr Han is supported by a Robert and Elizabeth Albert Travel Grant from the RACP Foundation, Australia. Dr Steinberg has reported that he has no relationships relevant to the contents of this paper to disclose.
- Arrhythmias, Cardiac/complications, Brugada Syndrome/genetics, Death, Sudden, Cardiac/epidemiology, Heart Arrest/complications, Humans, Tachycardia, Ventricular/complications
Research areas
ID: 310912796