T-lymphocyte subsets in recurrent aphthous ulceration
Research output: Contribution to journal › Journal article › Research › peer-review
Peripheral T-lymphocyte subsets: T-helper (OKT4) and T-suppressor (OKT8) cells were studied quantitatively in 20 patients with recurrent aphthous ulceration (RAU) in ulcerative, as well as inactive, stages of the disease. The figures were compared with T-lymphocyte subsets from matched control donors with no history of RAU. The ratio of T-helper: T-suppressor cells was significantly lower in both stages in the patients compared with controls due to a significantly increased number of T-suppressor cells in RAU patients. The number of T-helper cells in the patients did not differ significantly in either stage compared with controls. The study support the hypothesis of recurrent aphthous ulceration being a disorder of immunodeficiency.
Original language | English |
---|---|
Journal | Journal of Oral Pathology & Medicine |
Volume | 18 |
Issue number | 1 |
Pages (from-to) | 59-60 |
Number of pages | 2 |
ISSN | 0904-2512 |
Publication status | Published - Jan 1989 |
- Adolescent, Adult, Aged, Female, Humans, Leukocyte Count, Male, Middle Aged, Recurrence, Stomatitis, Aphthous, T-Lymphocytes, T-Lymphocytes, Helper-Inducer, T-Lymphocytes, Regulatory
Research areas
ID: 44515047