Kristian Linnet

Kristian Linnet

Professor


  1. 2017
  2. Published

    Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH

    Nielsen, L. M., Holm, N. B., Leth-Petersen, S., Kristensen, Jesper Langgaard, Olsen, L. & Linnet, Kristian, 2017, In: Drug Testing and Analysis. 9, 5, p. 671–679

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. Published

    Targeted analysis of 116 drugs in hair by UHPLC-MS/MS and its application to forensic cases

    Wang, X., Johansen, Sys Stybe, Nielsen, Marie Katrine Klose & Linnet, Kristian, 2017, In: Drug Testing and Analysis. 9, 8, p. 1137–1151

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2016
  6. Published

    Determination of the unbound fraction of R- and S-methadone in human brain

    Holm, K. M. D. & Linnet, Kristian, Nov 2016, In: International Journal of Legal Medicine (Print). 130, 6, p. 1519–1526

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Nitrobenzodiazepines: Postmortem brain and blood reference concentrations

    Skov, L., Holm, K. M. D. & Linnet, Kristian, Nov 2016, In: Forensic Science International. 268, p. 39-45 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    JWH-018 ω-OH, a shared hydroxy metabolite of the two synthetic cannabinoids JWH-018 and AM-2201, undergoes oxidation by alcohol dehydrogenase and aldehyde dehydrogenase enzymes in vitro forming the carboxylic acid metabolite

    Holm, N. B., Noble, C. & Linnet, Kristian, 30 Sep 2016, In: Toxicology Letters. 259, p. 35-43 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Postmortem Brain and Blood Reference Concentrations of Alprazolam, Bromazepam, Chlordiazepoxide, Diazepam, and their Metabolites and a Review of the Literature

    Skov, L., Holm, K. M. D., Johansen, Sys Stybe & Linnet, Kristian, Sep 2016, In: Journal of Analytical Toxicology. 40, 7, p. 529-536 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Cytochrome P450-mediated metabolism of the synthetic cannabinoids UR-144 and XLR-11

    Nielsen, L. M., Holm, N. B., Olsen, L. & Linnet, Kristian, Aug 2016, In: Drug Testing and Analysis. 8, 8, p. 792–800

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Methadone-Related Overdose Deaths in a Liberal Opioid Maintenance Treatment Programme

    Tjagvad, C., Skurtveit, S., Linnet, Kristian, Andersen, L. V., Christoffersen, D. J. & Clausen, T., Aug 2016, In: European Addiction Research. 22, 5, p. 249-258 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A case story, involving the use of maltitol, a sugar alcohol, as a cutting agent in amphetamine and cocaine powders

    Reitzel, Lotte Ask, Holm, N. B., Linnet, Kristian & Müller, Irene Breum, Jun 2016, In: Scandinavian Journal of Forensic Science. 22, 1, p. 6-10 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Psychiatric disorders are overlooked in patients with drug abuse

    Kruckow, L., Linnet, Kristian & Banner, Jytte, Mar 2016, In: Danish Medical Journal. 63, 3, A5207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Development of a UPLC–MS/MS method for determining ɣ-hydroxybutyric acid (GHB) and GHB glucuronide concentrations in hair and application to forensic cases

    Wang, X., Johansen, Sys Stybe & Linnet, Kristian, Jan 2016, In: Forensic Toxicology. 34, 1, p. 51-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2015
  16. Published

    Fatal poisoning among patients with drug addiction

    Simonsen, Kirsten Wiese, Christoffersen, D. J., Banner, Jytte, Linnet, Kristian & Andersen, L. V., Oct 2015, In: Danish Medical Journal. 62, 10, p. 1-5 5 p., A5147.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    CYP3A4 Mediates Oxidative Metabolism of the Synthetic Cannabinoid AKB-48

    Holm, N. B., Nielsen, L. M. & Linnet, Kristian, Sep 2015, In: A A P S Journal. 17, 5, p. 1237-2345 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Synthetic cannabimimetic agents metabolized by carboxylesterases

    Thomsen, Ragnar, Nielsen, L. M., Holm, N. B., Rasmussen, H. B., Linnet, Kristian & INDICES Consortium, I. C., Jul 2015, In: Drug Testing and Analysis. 7, 7, p. 565-76 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics

    Rasmussen, Henrik Berg, Bjerre, D., Linnet, Kristian, Jürgens, G., Dalhoff, Kim, Stefansson, H., Hankemeier, T., Kaddurah-Daouk, R., Taboureau, O., Brunak, Søren, Houmann, T., Jeppesen, Pia, Pagsberg, Anne Katrine, Plessen, K., Dyrborg, J., Hansen, Peter Riis, Hansen, P. E., Hughes, T., Werge, Thomas & INDICES Consortium, I. C., Apr 2015, In: Pharmacogenomics. 16, 6, p. 649-65

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Evaluation of poly-drug use in methadone-related fatalities using segmental hair analysis

    Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Linnet, Kristian, Mar 2015, In: Forensic Science International. 248, p. 134–139 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Metabolites of 5F-AKB-48, a synthetic cannabinoid receptor agonist, identified in human urine and liver microsomal preparations using liquid chromatography high-resolution mass spectrometry

    Holm, N. B., Pedersen, A. J., Dalsgaard, Petur Weihe & Linnet, Kristian, Mar 2015, In: Drug Testing and Analysis. 7, 3, p. 199-206 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Distribution of Enantiomers of Methadone and Its Main Metabolite EDDP in Human Tissues and Blood of Postmortem Cases

    Holm, K. M. D. & Linnet, Kristian, Jan 2015, In: Journal of Forensic Sciences. 60, 1, p. 95-101 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Postmortem Femoral Blood Reference Concentrations of Aripiprazole, Chlorprothixene, and Quetiapine

    Skov, L., Johansen, Sys Stybe & Linnet, Kristian, Jan 2015, In: Journal of Analytical Toxicology. 39, 1, p. 41-44 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Postmortem Quetiapine Reference Concentrations in Brain and Blood

    Skov, L., Johansen, Sys Stybe & Linnet, Kristian, 2015, In: Journal of Analytical Toxicology. 39, 7, p. 557-561 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Selection and Analytical Evaluation of Methods — With Statistical Techniques

    Linnet, Kristian & Boyd, J. C., 2015, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7 ed. p. 6-32 27 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  26. 2014
  27. Published

    Identification of peptide and protein doping related drug compounds confiscated in Denmark between 2007-2013

    Hartvig, R. A., Holm, N. B., Dalsgaard, Petur Weihe, Reitzel, Lotte Ask, Müller, Irene Breum & Linnet, Kristian, Dec 2014, In: Scandinavian Journal of Forensic Science. 20, 2, p. 42-49 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The Ratio of 6β-Hydroxycortisol to Cortisol in Urine as a Measure of Cytochrome P450 3A Activity in Postmortem Cases

    Lang, L. M. & Linnet, Kristian, Jul 2014, In: Journal of Forensic Sciences. 59, 4, p. 1036-40 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    In Vitro Drug Metabolism by Human Carboxylesterase 1: Focus on Angiotensin-Converting Enzyme Inhibitors

    Thomsen, Ragnar, Rasmussen, H. B., Linnet, Kristian & INDICES Consortium, I. C., Jan 2014, In: Drug Metabolism and Disposition. 42, 1, p. 126-33 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Postmortem Femoral Blood Concentrations of Risperidone

    Linnet, Kristian & Johansen, Sys Stybe, Jan 2014, In: Journal of Analytical Toxicology. 38, 1, p. 57-60 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Pre-analytical and analytical variation of drug determination in segmented hair using ultra-performance liquid chromatography-tandem mass spectrometry

    Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Linnet, Kristian, Jan 2014, In: Forensic Science International. 234, p. 16-21 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Prediction of cytochrome p450 mediated metabolism of designer drugs

    Nielsen, L. M., Linnet, Kristian, Olsen, L. & Rydberg, P., 2014, In: Current Topics in Medicinal Chemistry. 14, 11, p. 1365-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Screening for Anabolic Steroids in Urine of Forensic Cases Using Fully Automated Solid Phase Extraction and LC–MS-MS

    Andersen, D. W. & Linnet, Kristian, 2014, In: Journal of Analytical Toxicology. 38, 9, p. 637-44 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2013
  35. Published

    Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark

    Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Linnet, Kristian, 1 Dec 2013, In: Drug and Alcohol Dependence. 133, 2, p. 447-51 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    In vitro metabolism and pharmacokinetic studies on methylone

    Pedersen, A. J., Petersen, T. H. & Linnet, Kristian, Jun 2013, In: Drug Metabolism and Disposition. 41, 6, p. 1247-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    In vitro metabolism studies on mephedrone and analysis of forensic cases

    Pedersen, A. J., Reitzel, Lotte Ask, Johansen, Sys Stybe & Linnet, Kristian, Jun 2013, In: Drug Testing and Analysis. 5, 6, p. 430-438

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The frequency of drugs in randomly selected drivers in Denmark.

    Simonsen, Kirsten Wiese, Steentoft, A., Hels, T., Bernhoft, I. M., Rasmussen, Brian Schou & Linnet, Kristian, Jun 2013. 1 p.

    Research output: Contribution to conferencePosterResearch

  39. Published

    Screening for illicit and medicinal drugs in whole blood using fully automated SPE and UHPLC-TOF-MS with data-independent acquisition

    Pedersen, A. J., Dalsgaard, Petur Weihe, Rode, A. J., Rasmussen, Brian Schou, Müller, Irene Breum, Johansen, Sys Stybe & Linnet, Kristian, 22 Apr 2013, In: Journal of Separation Science. 36, 13, p. 2081-2089

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Screening of 30 acidic and neutral pharmaceuticals in whole blood by fully automated SPE and UPLC-TOF-MS(E.)

    Dalsgaard, Petur Weihe, Rode, A. J., Pedersen, A. J., Rasmussen, Brian Schou, Windberg, C. N. & Linnet, Kristian, Apr 2013, In: Drug Testing and Analysis. 5, 4, p. 254-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Quantification of 31 illicit and medicinal drugs and metabolites in whole blood by fully automated solid-phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry

    Bjørk, M. K., Simonsen, Kirsten Wiese, Andersen, D. W., Dalsgaard, Petur Weihe, Sigurdardottir, S., Linnet, Kristian & Rasmussen, Brian Schou, 8 Jan 2013, In: Analytical and Bioanalytical Chemistry. 405, p. 2607-2617 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Measurement procedure comparison and bias estimation using subject samples, EP09-A3, CLSI document, 2013

    Budd, J., Durham, A., Gwise, T., Iriarte, B., Kallner, A., Linnet, Kristian, Magari, R. & Vaks, J., 2013, Philadelphia, USA.

    Research output: Book/ReportReportCommissioned

  43. Published

    Postmortem urinary cortisol levels in relation to cause of death

    Lang, L. M. & Linnet, Kristian, 2013, In: Journal of Forensic Research. 4, 3, p. 1-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Psychoactive substances in seriously injured drivers in Denmark

    Simonsen, Kirsten Wiese, Steentoft, A., Bernhoft, I., Hels, T., Rasmussen, Brian Schou & Linnet, Kristian, 2013, In: Forensic Science International. 224, p. 44-50 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Quantitative Analysis of 30 Drugs in Whole Blood by SPE and UHPLC-TOF-MS

    Dalsgaard, Petur Weihe, Rode, A. J., Rasmussen, Brian Schou, Bjork, M. K., Petersen, D. I., Madsen, K. A., Gammelgaard, Bente, Simonsen, Kirsten Wiese & Linnet, Kristian, 2013, In: Journal of Forensic Science and Criminology. 1, 1, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Quantitative analysis of 30 drugs in whole blood by SPE and UHPLC-TOF-MS

    Dalsgaard, Petur Weihe, Rode, A. J., Rasmussen, Brian Schou, Bjørk, M. K., Petersen, D., Madsen, K., Gammelgaard, Bente, Simonsen, Kirsten Wiese & Linnet, Kristian, 2013, In: Journal of Forensic Science and Criminology. 1, 1, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Quantitative analysis of cortisol and 6beta-hydroxycortisol in urine by fully automated SPE and ultra-performance LC coupled with electrospray and atmospheric pressure Chemical ionization (ESCi)-TOF-MS

    Lang, L. M., Dalsgaard, Petur Weihe & Linnet, Kristian, 2013, In: Journal of Separation Science. 36, p. 246-251 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Screening of Danish traffic cases for synthetic cannabinoids in whole blood by LC-MS/MS

    Holm, N. B., Pineda, R., Andersen, D. W., Rasmussen, Brian Schou, Dalsgaard, Petur Weihe, Hoegberg, L., Johansen, Sys Stybe & Linnet, Kristian, 2013, In: Scandinavian Journal of Forensic Science. 19, 2, p. 31-37 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2012
  50. Published

    Beyond diagnostic accuracy: the clinical utility of diagnostic tests.

    Bossuyt, P., Reitsma, J., Linnet, Kristian & Moons, K., Dec 2012, In: Clinical Chemistry. 58, 12, p. 1636-1643 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Systematic reviews of studies quantifying the accuracy of diagnostic tests and markers.

    Reitsma, J., Moons, K., Bossuyt, P. & Linnet, Kristian, Nov 2012, In: Clinical Chemistry. 58, 11, p. 1534-1545 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Chiral Analysis of Methadone and its Main Metabolite, EDDP, in Postmorten Brain and Blood by Automated SPE and Liquid Chromatography-Mass Spectrometry

    Holm, K. M. D. & Linnet, Kristian, Sep 2012, In: Journal of Analytical Toxicology. 36, 21, p. 487-496 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Presence of psychoactive substances in oral fluid from randomly selected drivers in Denmark.

    Simonsen, Kirsten Wiese, Steentoft, A., Hels, T., Bernhoft, I. M., Rasmussen, Brian Schou & Linnet, Kristian, 29 Jul 2012, In: Forensic Science International. 221, p. 33-38 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Quantifying the added value of a diagnostic test or marker

    Moons, K., de Groot, J., Linnet, Kristian, Reitsma, J. & Bossuyt, P., Jan 2012, In: Clinical Chemistry. 58, 10, p. 1408-1417 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Breath alcohol analysis incorporating standardization to water vapour is as precise as blood alcohol analysis

    Grubb, D., Rasmussen, Brian Schou, Linnet, Kristian, Olsson, S. & Lindberg , L., 2012, In: Forensic Science International. 216, p. 88-91 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Enantioselective Determination of Methylphenidate and Ritalinic Acid in Whole Blood from Forensic Cases Using Automated Solid-Phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry

    Thomsen, Ragnar, Rasmussen, H. B., Linnet, Kristian & the INDICES Consortium, T. I. C., 2012, In: Journal of Analytical Toxicology. 36, 8, p. 560-568 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Lack of interaction between sertraline and lamotrigine in psychiatric patients: a retrospective study.

    Christensen, J., Sandgaard, A., Sidenius, P., Linnet, Kristian & Licht, R., 2012, In: Pharmacopsychiatry. 45, p. 119-121 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Postmortem drug concentration intervals for the non-intoxicated state - A review

    Linnet, Kristian, 2012, In: Journal of Clinical Forensic and Legal Medicine. 19, 5, p. 245-249 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  59. Published

    Quantifying the accuracy of a diagnostic test or marker

    Linnet, Kristian, Bossuyt, P., Moons, K. & Reitsma, J., 2012, In: Clinical Chemistry. 58, 9, p. 1292-1301 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Re: Grubb et al., Breath alcohol analysis incorporating standardization to water vapour is as precise as blood alcohol analysis. Forens. Sci. Int. 216 (2012) 88-91

    Grubb, D., Lindberg, L., Rasmussen, Brian Schou, Linnet, Kristian & Olsson, S. G., 2012, In: Forensic Science International. 223, 1-3, p. e62-e63

    Research output: Contribution to journalLetterResearchpeer-review

  61. Published

    Selection and and analytical evaluation of methods - with statistical techniques

    Linnet, Kristian & Boyd, J., 2012, Tietz textbook of clinical chemistry and molecular diagnostics 5. ed.. St Louis: Elsevier Sci. Intl. Congress Series 1100, p. 7-48 41 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  62. Published

    Toxicological screening of basic drugs in whole blood using UPLC-TOF-MS

    Dalsgaard, Petur Weihe, Rasmussen, Brian Schou, Müller, Irene Breum & Linnet, Kristian, 2012, In: Drug Testing and Analysis. 4, 5, p. 313-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Validation of a fully automated robotic setup for preparation of whole blood samples for LC-MS toxicology analysis

    Andersen, D. W., Rasmussen, Brian Schou & Linnet, Kristian, 2012, In: Journal of Analytical Toxicology. 36, 4, p. 280-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. 2011
  65. Published

    Forgiftningsdødsfald blandt narkomaner i 2007

    Simonsen, Kirsten Wiese, Hansen, A. C., Rollmann, D., Kringsholm, B., Müller, Irene Breum, Johansen, Sys Stybe & Linnet, Kristian, 29 Aug 2011, In: Ugeskrift for Laeger. 173, 35, p. 2118 1 p.

    Research output: Contribution to journalConference articleResearch

  66. Published

    Drug-related death in Denmark in 2007

    Simonsen, Kirsten Wiese, Hansen, A. C., Rollmann, D., Kringsholm, B., Müller, Irene Breum, Johansen, Sys Stybe & Linnet, Kristian, 1 Aug 2011, In: Danish Medical Bulletin (Online). 58, 8, p. 1-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Postmortem femoral blood concentrations of amlodipine

    Linnet, Kristian & Johansen, Sys Stybe, Jan 2011, In: Journal of Analytical Toxicology. 35, p. 227-231 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Risk assessment of accidental nortriptyline poisoning: the importance of cytochrome P450 for nortriptyline elimination investigated using a population-based pharmacokinetic simulator.

    Jornil, J., Jensen, K. G., Larsen, F. & Linnet, Kristian, 2011, In: European Journal of Pharmaceutical Sciences. 44, 3, p. 265-272

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Venovenøs hæmodiafiltrering til baclofenforgiftet patient

    Nielsen, S. U., Jansen, T., Johansen, Sys Stybe, Linnet, Kristian, Gregersen, P. & Høgberg, L. C. G., 2011, In: Ugeskrift for Laeger. 173, 22, p. 1578-9 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. 2010
  71. Published

    The frequency of drugs among Danish drivers before and after the introduction of fixed concentration limits

    Steentoft, A., Simonsen, Kirsten Wiese & Linnet, Kristian, Aug 2010, In: Traffic Injury Prevention. 11, 4, p. 329-33 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Determination of 19 drugs of abuse and metabolites in whole blood by high-performance liquid chromatography-tandem mass spectrometry

    Bjørk, M. K., Nielsen, Marie Katrine Klose, Markussen, L. Ø., Klinke, H. B. & Linnet, Kristian, Apr 2010, In: Analytical and Bioanalytical Chemistry. 396, 7, p. 2393-401 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published
  74. Published

    Determination of ketone bodies in blood by headspace gas chromatography-mass spectrometry

    Holm, K. M. D., Linnet, Kristian, Rasmussen, Brian Schou & Pedersen, A. J., Jan 2010, In: Journal of Analytical Toxicology. 34, 9, p. 549-54 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Screening and quantitative determination of twelve acidic and neutral pharmaceuticals in whole blood by liquid-liquid extraction and liquid chromatography-tandem mass spectrometry

    Simonsen, Kirsten Wiese, Steentoft, A., Buck, M., Hansen, L. & Linnet, Kristian, Jan 2010, In: Journal of Analytical Toxicology. 34, 7, p. 367-73 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Identification of cytochrome P450 isoforms involved in the metabolism of paroxetine and estimation of their importance for human paroxetine metabolism using a population-based simulator

    Jornil, J., Jensen, K. G., Larsen, F. & Linnet, Kristian, 2010, In: Drug Metabolism and Disposition. 38, 3, p. 376-85 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Postmortem Blood Concentrations of R- and S-Enantiomers of Methadone and EDDP in Drug Users: Influence of Co-Medication and P-glycoprotein Genotype

    Buchard, Anders, Linnet, Kristian, Johansen, Sys Stybe, Munkholm, Julie, Fregerslev, M. & Morling, Niels, 2010, In: Journal of Forensic Sciences. 55, 2, p. 457-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Simultaneous screening and quantification of 52 common pharmaceuticals and drugs of abuse in hair using UPLC-TOF-MS

    Nielsen, Marie Katrine Klose, Johansen, Sys Stybe, Dalsgaard, Petur Weihe & Linnet, Kristian, 2010, In: Forensic Science International. 196, 1-3, p. 85-92 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. 2009
  80. Published

    Blood concentrations of clonazepam and 7-amino-clonazepam in forensic cases in Denmark for the period 2002-2007

    Steentoft, A. & Linnet, Kristian, 2009, In: Forensic Science International. 184, p. 74-79 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Roles of polymorphic enzymes CYP2D6 and CYP2C19 for in vitro metabolism of amitriptyline at therapeutic and toxic levels

    Jornil, J. & Linnet, Kristian, 2009, In: Forensic Toxicology. 27, p. 12-20 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Simultaneous screening and quantification of 29 drugs of abuse in oral fluid by solid-phase extraction and ultraperformance LC-MS/MS

    Badawi, N., Simonsen, Kirsten Wiese, Steentoft, A., Bernhoft, I. M. & Linnet, Kristian, 2009, In: Clinical Chemistry. 55, 11, p. 2004-18 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. 2008
  84. Published

    Chiral analysis of methadone and its main metabolite EDDP in postmortem blood by liquid chromatography-mass spectrometry

    Johansen, Sys Stybe & Linnet, Kristian, Sep 2008, In: Journal of Analytical Toxicology. 32, 7, p. 499–504

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Reliability of self-reported use of amphetamine, barbiturates, benzodiazepines, cannabinoids, cocaine, methadone, and opiates among acutely hospitalized elderly medical patients

    Glintborg, B., Olsen, L., Poulsen, H., Linnet, Kristian, Dalhoff, Kim, Glintborg, B., Olsen, L. H., Poulsen, Henrik Enghusen, Linnet, K. & Dalhoff, K. P., 1 Mar 2008, In: Clinical Toxicology. 46, 3, p. 239-42 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs

    Linnet, Kristian & Ejsing, T. B., 2008, In: European Neuropsychopharmacology. 18, 3, p. 157-169 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    An oxcarbazepine-related fatality with an overview of 26 oxcarbazepine postmortem cases.

    Linnet, Kristian, Steentoft, A., Simonsen, Kirsten Wiese, Sabers, A. & Hansen, Steen Holger, 2008, In: Forensic Science International. 177, 2-3, p. 248-251 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Analytical validation of methods - With statistical methods.

    Linnet, Kristian & Boyd, J., 2008, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics.. Burtis, C., Ashwood, ER. & Bruns, D. (eds.). 6 ed. New York: Elsevier, p. 201-228 28 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  89. Published

    Chiral analysis of methadone and its main metabolite EDDP in postmortem blood by liquid chromatography-mass spectrometry

    Johansen, Sys Stybe & Linnet, Kristian, 2008, In: Journal of Analytical Toxicology. 32, 7, p. 499-504 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Dominance of pre-analytical over analytical variation for measurement of methadone and its main metabolite in postmortem femoral blood

    Linnet, Kristian, Johansen, Sys Stybe, Buchard, Anders, Munkholm, Julie & Morling, Niels, 2008, In: Forensic Science International. 179, 1, p. 78-82 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. 2007
  92. Published

    A review on the relation between the brain-serum concentration ratio of drugs and the influence of P-glycoprotein

    Ejsing, T. B., Morling, Niels & Linnet, Kristian, 2007, In: Drug Metabolism and Drug Interactions. 22, 2-3, p. 113-29 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Euforiserende stoffer i trafikken

    Linnet, Kristian & Steentoft, A., 2007, In: Ugeskrift for læger. 169, 46, p. 3946-3949 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Performance of four mixed-mode solid-phase extraction columns applied to basic drugs in urine

    Klinke, H. B. & Linnet, Kristian, 2007, In: Scandinavian Journal of Clinical & Laboratory Investigation. 67, 7, p. 778-782 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. 2006
  96. Published

    In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions

    Hasselstøm, J. & Linnet, Kristian, 6 Jul 2006, In: Drug Metabolism and Drug Interactions. 21, 3-4, p. 187-211 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    [Forensic chemistry: analytical developments and pharmacological aspects].

    Linnet, Kristian, Mar 2006, In: Ugeskrift for læger.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Analytical validation of methods - With statistical methods

    Linnet, Kristian, Boyd, J. C., Burtis, C., Ashwood, E. R. & Bruns, D., 2006, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 4 ed. New York: W. B. Saunders Company, p. 353-407 54 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  99. Published

    In vitro studies of quetiapine metabolism using the sunstrate depletion approach with focus on drug-drug interactions

    Hasselstrøm, J. & Linnet, Kristian, 2006, In: Drug Metabolism and Drug Interactions. Vol.21, No.3-4, p. 187-211

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Retskemi-Analytiske udviklingstendenser og farmakologiske aspekter

    Linnet, Kristian, 2006, In: Ugeskrift for læger. 168/11, p. 1114-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Selection and Analytical Evaluations of Methods-With Statistical Techniques

    Linnet, Kristian & Boyd, J. C., 2006, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 4.ed. ed. New York, p. 353-407

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  102. Published

    The exponentially weighted moving average (EWMA) rule compared with traditionally used quality control rules

    Linnet, Kristian, 2006, In: Clinical Chemistry and Laboratory Medicine. 44, 4, p. 396-399 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    The influence of P-glycoprotein on cerebral and hepatic concentrations of nortriptyline and its metabolites

    Ejsing, T. B., Hasselstrøm, J. & Linnet, Kristian, 2006, In: Drug Metabolism and Drug Interactions. 21, p. 139-162

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. 2005
  105. Published

    Estimation of the limit of detection with a bootstrap-derived standard error by a partly non-parametric approach. Application to HPLC drug assays

    Linnet, Kristian, 2005, In: Clinical Chemistry and Laboratory Medicine. 43, 4, p. 394-399

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Influence of P-glycoprotein inhibition on the distribution of the tricyclic antidepressant nortriptyline over the blood-brain barrier

    Ejsing, T. B. & Linnet, Kristian, 2005, In: Human Psychopharmacology. 20, 2, p. 149-153

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    P-glycoprotein interaction with risperidone and 9-OH-risperidone studied in vitro, in knock-out mice and in drug-drug interaction experiments

    Ejsing, T. B., Pedersen, A. D. & Linnet, Kristian, 2005, In: Human Psychopharmacology 2005. 20, 7, p. 493-500

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. 2004
  109. Published

    [Comments to the brochure "Genetic tests and drug monitoring" distributed by the Laboratoriet, Epilepsihospitalet in Dianalund].

    Linnet, Kristian, Jan 2004, In: Ugeskrift for læger.

    Research output: Contribution to journalJournal articleCommunication

  110. Published

    A review on the influence of the drug transporter P-glycoprotein on the distribution of drugs over the blood-brain barrier

    Linnet, Kristian, 2004, In: Recent Research Developments in Drug Metabolism and Disposition. 2, p. 15-26

    Research output: Contribution to journalReviewResearch

  111. Published

    An overview on the metabolism of some frequently used antidepressants with focus on involved cytochrome P450 enzymes

    Linnet, Kristian, 2004, In: Current Topics in Pharmacology. 8, p. 137-148 12 p.

    Research output: Contribution to journalReviewResearch

  112. Published

    In vitro microsomal metabolism of imipramine under conditions mimicking the in vivo steady-state situation

    Linnet, Kristian, 2004, In: Human Psychopharmacology: Clinical and Experimental. 19, p. 31-36 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Kommentarer til brochuren "Genetiske tests og lægemiddelmonitorering uddelt af laboratoriet, Epilepsihospitalet i Dianalund

    Linnet, Kristian, 2004, In: Ugeskrift for læger. 166, p. 70-71 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  114. Published

    Partly nonparametric approach for determining the limit of detection

    Linnet, Kristian & Kondratovich, M., 2004, In: Clinical Chemistry. 50, p. 732-740 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 3525