Kristian Linnet
Professor
Section of Forensic Chemistry
Frederik V's Vej 11
2100 København Ø
- 2017
- Published
Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH
Nielsen, L. M., Holm, N. B., Leth-Petersen, S., Kristensen, Jesper Langgaard, Olsen, L. & Linnet, Kristian, 2017, In: Drug Testing and Analysis. 9, 5, p. 671–679Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmortem concentrations of gamma-hydroxybutyrate (GHB) in peripheral blood and brain tissue - Differentiating between postmortem formation and antemortem intake
Thomsen, Ragnar, Rasmussen, Brian Schou, Johansen, Sys Stybe & Linnet, Kristian, 2017, In: Forensic Science International. 272, p. 154-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted analysis of 116 drugs in hair by UHPLC-MS/MS and its application to forensic cases
Wang, X., Johansen, Sys Stybe, Nielsen, Marie Katrine Klose & Linnet, Kristian, 2017, In: Drug Testing and Analysis. 9, 8, p. 1137–1151Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Determination of the unbound fraction of R- and S-methadone in human brain
Holm, K. M. D. & Linnet, Kristian, Nov 2016, In: International Journal of Legal Medicine (Print). 130, 6, p. 1519–1526Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitrobenzodiazepines: Postmortem brain and blood reference concentrations
Skov, L., Holm, K. M. D. & Linnet, Kristian, Nov 2016, In: Forensic Science International. 268, p. 39-45 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JWH-018 ω-OH, a shared hydroxy metabolite of the two synthetic cannabinoids JWH-018 and AM-2201, undergoes oxidation by alcohol dehydrogenase and aldehyde dehydrogenase enzymes in vitro forming the carboxylic acid metabolite
Holm, N. B., Noble, C. & Linnet, Kristian, 30 Sep 2016, In: Toxicology Letters. 259, p. 35-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmortem Brain and Blood Reference Concentrations of Alprazolam, Bromazepam, Chlordiazepoxide, Diazepam, and their Metabolites and a Review of the Literature
Skov, L., Holm, K. M. D., Johansen, Sys Stybe & Linnet, Kristian, Sep 2016, In: Journal of Analytical Toxicology. 40, 7, p. 529-536 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytochrome P450-mediated metabolism of the synthetic cannabinoids UR-144 and XLR-11
Nielsen, L. M., Holm, N. B., Olsen, L. & Linnet, Kristian, Aug 2016, In: Drug Testing and Analysis. 8, 8, p. 792–800Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methadone-Related Overdose Deaths in a Liberal Opioid Maintenance Treatment Programme
Tjagvad, C., Skurtveit, S., Linnet, Kristian, Andersen, L. V., Christoffersen, D. J. & Clausen, T., Aug 2016, In: European Addiction Research. 22, 5, p. 249-258 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A case story, involving the use of maltitol, a sugar alcohol, as a cutting agent in amphetamine and cocaine powders
Reitzel, Lotte Ask, Holm, N. B., Linnet, Kristian & Müller, Irene Breum, Jun 2016, In: Scandinavian Journal of Forensic Science. 22, 1, p. 6-10 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Psychiatric disorders are overlooked in patients with drug abuse
Kruckow, L., Linnet, Kristian & Banner, Jytte, Mar 2016, In: Danish Medical Journal. 63, 3, A5207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a UPLC–MS/MS method for determining ɣ-hydroxybutyric acid (GHB) and GHB glucuronide concentrations in hair and application to forensic cases
Wang, X., Johansen, Sys Stybe & Linnet, Kristian, Jan 2016, In: Forensic Toxicology. 34, 1, p. 51-60Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Fatal poisoning among patients with drug addiction
Simonsen, Kirsten Wiese, Christoffersen, D. J., Banner, Jytte, Linnet, Kristian & Andersen, L. V., Oct 2015, In: Danish Medical Journal. 62, 10, p. 1-5 5 p., A5147.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CYP3A4 Mediates Oxidative Metabolism of the Synthetic Cannabinoid AKB-48
Holm, N. B., Nielsen, L. M. & Linnet, Kristian, Sep 2015, In: A A P S Journal. 17, 5, p. 1237-2345 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthetic cannabimimetic agents metabolized by carboxylesterases
Thomsen, Ragnar, Nielsen, L. M., Holm, N. B., Rasmussen, H. B., Linnet, Kristian & INDICES Consortium, I. C., Jul 2015, In: Drug Testing and Analysis. 7, 7, p. 565-76 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics
Rasmussen, Henrik Berg, Bjerre, D., Linnet, Kristian, Jürgens, G., Dalhoff, Kim, Stefansson, H., Hankemeier, T., Kaddurah-Daouk, R., Taboureau, O., Brunak, Søren, Houmann, T., Jeppesen, Pia, Pagsberg, Anne Katrine, Plessen, K., Dyrborg, J., Hansen, Peter Riis, Hansen, P. E., Hughes, T., Werge, Thomas & INDICES Consortium, I. C., Apr 2015, In: Pharmacogenomics. 16, 6, p. 649-65Research output: Contribution to journal › Review › Research › peer-review
- Published
Evaluation of poly-drug use in methadone-related fatalities using segmental hair analysis
Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Linnet, Kristian, Mar 2015, In: Forensic Science International. 248, p. 134–139 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolites of 5F-AKB-48, a synthetic cannabinoid receptor agonist, identified in human urine and liver microsomal preparations using liquid chromatography high-resolution mass spectrometry
Holm, N. B., Pedersen, A. J., Dalsgaard, Petur Weihe & Linnet, Kristian, Mar 2015, In: Drug Testing and Analysis. 7, 3, p. 199-206 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of Enantiomers of Methadone and Its Main Metabolite EDDP in Human Tissues and Blood of Postmortem Cases
Holm, K. M. D. & Linnet, Kristian, Jan 2015, In: Journal of Forensic Sciences. 60, 1, p. 95-101 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmortem Femoral Blood Reference Concentrations of Aripiprazole, Chlorprothixene, and Quetiapine
Skov, L., Johansen, Sys Stybe & Linnet, Kristian, Jan 2015, In: Journal of Analytical Toxicology. 39, 1, p. 41-44 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmortem Quetiapine Reference Concentrations in Brain and Blood
Skov, L., Johansen, Sys Stybe & Linnet, Kristian, 2015, In: Journal of Analytical Toxicology. 39, 7, p. 557-561 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection and Analytical Evaluation of Methods — With Statistical Techniques
Linnet, Kristian & Boyd, J. C., 2015, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7 ed. p. 6-32 27 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2014
- Published
Identification of peptide and protein doping related drug compounds confiscated in Denmark between 2007-2013
Hartvig, R. A., Holm, N. B., Dalsgaard, Petur Weihe, Reitzel, Lotte Ask, Müller, Irene Breum & Linnet, Kristian, Dec 2014, In: Scandinavian Journal of Forensic Science. 20, 2, p. 42-49 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ratio of 6β-Hydroxycortisol to Cortisol in Urine as a Measure of Cytochrome P450 3A Activity in Postmortem Cases
Lang, L. M. & Linnet, Kristian, Jul 2014, In: Journal of Forensic Sciences. 59, 4, p. 1036-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro Drug Metabolism by Human Carboxylesterase 1: Focus on Angiotensin-Converting Enzyme Inhibitors
Thomsen, Ragnar, Rasmussen, H. B., Linnet, Kristian & INDICES Consortium, I. C., Jan 2014, In: Drug Metabolism and Disposition. 42, 1, p. 126-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmortem Femoral Blood Concentrations of Risperidone
Linnet, Kristian & Johansen, Sys Stybe, Jan 2014, In: Journal of Analytical Toxicology. 38, 1, p. 57-60 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pre-analytical and analytical variation of drug determination in segmented hair using ultra-performance liquid chromatography-tandem mass spectrometry
Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Linnet, Kristian, Jan 2014, In: Forensic Science International. 234, p. 16-21 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediction of cytochrome p450 mediated metabolism of designer drugs
Nielsen, L. M., Linnet, Kristian, Olsen, L. & Rydberg, P., 2014, In: Current Topics in Medicinal Chemistry. 14, 11, p. 1365-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening for Anabolic Steroids in Urine of Forensic Cases Using Fully Automated Solid Phase Extraction and LC–MS-MS
Andersen, D. W. & Linnet, Kristian, 2014, In: Journal of Analytical Toxicology. 38, 9, p. 637-44 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark
Nielsen, Marie Katrine Klose, Johansen, Sys Stybe & Linnet, Kristian, 1 Dec 2013, In: Drug and Alcohol Dependence. 133, 2, p. 447-51 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro metabolism and pharmacokinetic studies on methylone
Pedersen, A. J., Petersen, T. H. & Linnet, Kristian, Jun 2013, In: Drug Metabolism and Disposition. 41, 6, p. 1247-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro metabolism studies on mephedrone and analysis of forensic cases
Pedersen, A. J., Reitzel, Lotte Ask, Johansen, Sys Stybe & Linnet, Kristian, Jun 2013, In: Drug Testing and Analysis. 5, 6, p. 430-438Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The frequency of drugs in randomly selected drivers in Denmark.
Simonsen, Kirsten Wiese, Steentoft, A., Hels, T., Bernhoft, I. M., Rasmussen, Brian Schou & Linnet, Kristian, Jun 2013. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Screening for illicit and medicinal drugs in whole blood using fully automated SPE and UHPLC-TOF-MS with data-independent acquisition
Pedersen, A. J., Dalsgaard, Petur Weihe, Rode, A. J., Rasmussen, Brian Schou, Müller, Irene Breum, Johansen, Sys Stybe & Linnet, Kristian, 22 Apr 2013, In: Journal of Separation Science. 36, 13, p. 2081-2089Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of 30 acidic and neutral pharmaceuticals in whole blood by fully automated SPE and UPLC-TOF-MS(E.)
Dalsgaard, Petur Weihe, Rode, A. J., Pedersen, A. J., Rasmussen, Brian Schou, Windberg, C. N. & Linnet, Kristian, Apr 2013, In: Drug Testing and Analysis. 5, 4, p. 254-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of 31 illicit and medicinal drugs and metabolites in whole blood by fully automated solid-phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry
Bjørk, M. K., Simonsen, Kirsten Wiese, Andersen, D. W., Dalsgaard, Petur Weihe, Sigurdardottir, S., Linnet, Kristian & Rasmussen, Brian Schou, 8 Jan 2013, In: Analytical and Bioanalytical Chemistry. 405, p. 2607-2617 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement procedure comparison and bias estimation using subject samples, EP09-A3, CLSI document, 2013
Budd, J., Durham, A., Gwise, T., Iriarte, B., Kallner, A., Linnet, Kristian, Magari, R. & Vaks, J., 2013, Philadelphia, USA.Research output: Book/Report › Report › Commissioned
- Published
Postmortem urinary cortisol levels in relation to cause of death
Lang, L. M. & Linnet, Kristian, 2013, In: Journal of Forensic Research. 4, 3, p. 1-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Psychoactive substances in seriously injured drivers in Denmark
Simonsen, Kirsten Wiese, Steentoft, A., Bernhoft, I., Hels, T., Rasmussen, Brian Schou & Linnet, Kristian, 2013, In: Forensic Science International. 224, p. 44-50 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative Analysis of 30 Drugs in Whole Blood by SPE and UHPLC-TOF-MS
Dalsgaard, Petur Weihe, Rode, A. J., Rasmussen, Brian Schou, Bjork, M. K., Petersen, D. I., Madsen, K. A., Gammelgaard, Bente, Simonsen, Kirsten Wiese & Linnet, Kristian, 2013, In: Journal of Forensic Science and Criminology. 1, 1, p. 1-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative analysis of 30 drugs in whole blood by SPE and UHPLC-TOF-MS
Dalsgaard, Petur Weihe, Rode, A. J., Rasmussen, Brian Schou, Bjørk, M. K., Petersen, D., Madsen, K., Gammelgaard, Bente, Simonsen, Kirsten Wiese & Linnet, Kristian, 2013, In: Journal of Forensic Science and Criminology. 1, 1, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative analysis of cortisol and 6beta-hydroxycortisol in urine by fully automated SPE and ultra-performance LC coupled with electrospray and atmospheric pressure Chemical ionization (ESCi)-TOF-MS
Lang, L. M., Dalsgaard, Petur Weihe & Linnet, Kristian, 2013, In: Journal of Separation Science. 36, p. 246-251 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of Danish traffic cases for synthetic cannabinoids in whole blood by LC-MS/MS
Holm, N. B., Pineda, R., Andersen, D. W., Rasmussen, Brian Schou, Dalsgaard, Petur Weihe, Hoegberg, L., Johansen, Sys Stybe & Linnet, Kristian, 2013, In: Scandinavian Journal of Forensic Science. 19, 2, p. 31-37 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Beyond diagnostic accuracy: the clinical utility of diagnostic tests.
Bossuyt, P., Reitsma, J., Linnet, Kristian & Moons, K., Dec 2012, In: Clinical Chemistry. 58, 12, p. 1636-1643 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic reviews of studies quantifying the accuracy of diagnostic tests and markers.
Reitsma, J., Moons, K., Bossuyt, P. & Linnet, Kristian, Nov 2012, In: Clinical Chemistry. 58, 11, p. 1534-1545 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chiral Analysis of Methadone and its Main Metabolite, EDDP, in Postmorten Brain and Blood by Automated SPE and Liquid Chromatography-Mass Spectrometry
Holm, K. M. D. & Linnet, Kristian, Sep 2012, In: Journal of Analytical Toxicology. 36, 21, p. 487-496 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Presence of psychoactive substances in oral fluid from randomly selected drivers in Denmark.
Simonsen, Kirsten Wiese, Steentoft, A., Hels, T., Bernhoft, I. M., Rasmussen, Brian Schou & Linnet, Kristian, 29 Jul 2012, In: Forensic Science International. 221, p. 33-38 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantifying the added value of a diagnostic test or marker
Moons, K., de Groot, J., Linnet, Kristian, Reitsma, J. & Bossuyt, P., Jan 2012, In: Clinical Chemistry. 58, 10, p. 1408-1417 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breath alcohol analysis incorporating standardization to water vapour is as precise as blood alcohol analysis
Grubb, D., Rasmussen, Brian Schou, Linnet, Kristian, Olsson, S. & Lindberg , L., 2012, In: Forensic Science International. 216, p. 88-91 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enantioselective Determination of Methylphenidate and Ritalinic Acid in Whole Blood from Forensic Cases Using Automated Solid-Phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry
Thomsen, Ragnar, Rasmussen, H. B., Linnet, Kristian & the INDICES Consortium, T. I. C., 2012, In: Journal of Analytical Toxicology. 36, 8, p. 560-568 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of interaction between sertraline and lamotrigine in psychiatric patients: a retrospective study.
Christensen, J., Sandgaard, A., Sidenius, P., Linnet, Kristian & Licht, R., 2012, In: Pharmacopsychiatry. 45, p. 119-121 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmortem drug concentration intervals for the non-intoxicated state - A review
Linnet, Kristian, 2012, In: Journal of Clinical Forensic and Legal Medicine. 19, 5, p. 245-249 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Quantifying the accuracy of a diagnostic test or marker
Linnet, Kristian, Bossuyt, P., Moons, K. & Reitsma, J., 2012, In: Clinical Chemistry. 58, 9, p. 1292-1301 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Re: Grubb et al., Breath alcohol analysis incorporating standardization to water vapour is as precise as blood alcohol analysis. Forens. Sci. Int. 216 (2012) 88-91
Grubb, D., Lindberg, L., Rasmussen, Brian Schou, Linnet, Kristian & Olsson, S. G., 2012, In: Forensic Science International. 223, 1-3, p. e62-e63Research output: Contribution to journal › Letter › Research › peer-review
- Published
Selection and and analytical evaluation of methods - with statistical techniques
Linnet, Kristian & Boyd, J., 2012, Tietz textbook of clinical chemistry and molecular diagnostics 5. ed.. St Louis: Elsevier Sci. Intl. Congress Series 1100, p. 7-48 41 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Toxicological screening of basic drugs in whole blood using UPLC-TOF-MS
Dalsgaard, Petur Weihe, Rasmussen, Brian Schou, Müller, Irene Breum & Linnet, Kristian, 2012, In: Drug Testing and Analysis. 4, 5, p. 313-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of a fully automated robotic setup for preparation of whole blood samples for LC-MS toxicology analysis
Andersen, D. W., Rasmussen, Brian Schou & Linnet, Kristian, 2012, In: Journal of Analytical Toxicology. 36, 4, p. 280-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Forgiftningsdødsfald blandt narkomaner i 2007
Simonsen, Kirsten Wiese, Hansen, A. C., Rollmann, D., Kringsholm, B., Müller, Irene Breum, Johansen, Sys Stybe & Linnet, Kristian, 29 Aug 2011, In: Ugeskrift for Laeger. 173, 35, p. 2118 1 p.Research output: Contribution to journal › Conference article › Research
- Published
Drug-related death in Denmark in 2007
Simonsen, Kirsten Wiese, Hansen, A. C., Rollmann, D., Kringsholm, B., Müller, Irene Breum, Johansen, Sys Stybe & Linnet, Kristian, 1 Aug 2011, In: Danish Medical Bulletin (Online). 58, 8, p. 1-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmortem femoral blood concentrations of amlodipine
Linnet, Kristian & Johansen, Sys Stybe, Jan 2011, In: Journal of Analytical Toxicology. 35, p. 227-231 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk assessment of accidental nortriptyline poisoning: the importance of cytochrome P450 for nortriptyline elimination investigated using a population-based pharmacokinetic simulator.
Jornil, J., Jensen, K. G., Larsen, F. & Linnet, Kristian, 2011, In: European Journal of Pharmaceutical Sciences. 44, 3, p. 265-272Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Venovenøs hæmodiafiltrering til baclofenforgiftet patient
Nielsen, S. U., Jansen, T., Johansen, Sys Stybe, Linnet, Kristian, Gregersen, P. & Høgberg, L. C. G., 2011, In: Ugeskrift for Laeger. 173, 22, p. 1578-9 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
The frequency of drugs among Danish drivers before and after the introduction of fixed concentration limits
Steentoft, A., Simonsen, Kirsten Wiese & Linnet, Kristian, Aug 2010, In: Traffic Injury Prevention. 11, 4, p. 329-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of 19 drugs of abuse and metabolites in whole blood by high-performance liquid chromatography-tandem mass spectrometry
Bjørk, M. K., Nielsen, Marie Katrine Klose, Markussen, L. Ø., Klinke, H. B. & Linnet, Kristian, Apr 2010, In: Analytical and Bioanalytical Chemistry. 396, 7, p. 2393-401 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A validated method for simultaneous screening and quantification of twenty-three benzodiazepines and metabolites plus zopiclone and zaleplone in whole blood by liquid-liquid extraction and ultra-performance liquid chromatography- tandem mass spectrometry
Simonsen, Kirsten Wiese, Hermansson, S., Steentoft, A. & Linnet, Kristian, Jan 2010, In: Journal of Analytical Toxicology. 34, 6, p. 332-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of ketone bodies in blood by headspace gas chromatography-mass spectrometry
Holm, K. M. D., Linnet, Kristian, Rasmussen, Brian Schou & Pedersen, A. J., Jan 2010, In: Journal of Analytical Toxicology. 34, 9, p. 549-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening and quantitative determination of twelve acidic and neutral pharmaceuticals in whole blood by liquid-liquid extraction and liquid chromatography-tandem mass spectrometry
Simonsen, Kirsten Wiese, Steentoft, A., Buck, M., Hansen, L. & Linnet, Kristian, Jan 2010, In: Journal of Analytical Toxicology. 34, 7, p. 367-73 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of cytochrome P450 isoforms involved in the metabolism of paroxetine and estimation of their importance for human paroxetine metabolism using a population-based simulator
Jornil, J., Jensen, K. G., Larsen, F. & Linnet, Kristian, 2010, In: Drug Metabolism and Disposition. 38, 3, p. 376-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmortem Blood Concentrations of R- and S-Enantiomers of Methadone and EDDP in Drug Users: Influence of Co-Medication and P-glycoprotein Genotype
Buchard, Anders, Linnet, Kristian, Johansen, Sys Stybe, Munkholm, Julie, Fregerslev, M. & Morling, Niels, 2010, In: Journal of Forensic Sciences. 55, 2, p. 457-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous screening and quantification of 52 common pharmaceuticals and drugs of abuse in hair using UPLC-TOF-MS
Nielsen, Marie Katrine Klose, Johansen, Sys Stybe, Dalsgaard, Petur Weihe & Linnet, Kristian, 2010, In: Forensic Science International. 196, 1-3, p. 85-92 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Blood concentrations of clonazepam and 7-amino-clonazepam in forensic cases in Denmark for the period 2002-2007
Steentoft, A. & Linnet, Kristian, 2009, In: Forensic Science International. 184, p. 74-79 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of polymorphic enzymes CYP2D6 and CYP2C19 for in vitro metabolism of amitriptyline at therapeutic and toxic levels
Jornil, J. & Linnet, Kristian, 2009, In: Forensic Toxicology. 27, p. 12-20 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous screening and quantification of 29 drugs of abuse in oral fluid by solid-phase extraction and ultraperformance LC-MS/MS
Badawi, N., Simonsen, Kirsten Wiese, Steentoft, A., Bernhoft, I. M. & Linnet, Kristian, 2009, In: Clinical Chemistry. 55, 11, p. 2004-18 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Chiral analysis of methadone and its main metabolite EDDP in postmortem blood by liquid chromatography-mass spectrometry
Johansen, Sys Stybe & Linnet, Kristian, Sep 2008, In: Journal of Analytical Toxicology. 32, 7, p. 499–504Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reliability of self-reported use of amphetamine, barbiturates, benzodiazepines, cannabinoids, cocaine, methadone, and opiates among acutely hospitalized elderly medical patients
Glintborg, B., Olsen, L., Poulsen, H., Linnet, Kristian, Dalhoff, Kim, Glintborg, B., Olsen, L. H., Poulsen, Henrik Enghusen, Linnet, K. & Dalhoff, K. P., 1 Mar 2008, In: Clinical Toxicology. 46, 3, p. 239-42 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs
Linnet, Kristian & Ejsing, T. B., 2008, In: European Neuropsychopharmacology. 18, 3, p. 157-169 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An oxcarbazepine-related fatality with an overview of 26 oxcarbazepine postmortem cases.
Linnet, Kristian, Steentoft, A., Simonsen, Kirsten Wiese, Sabers, A. & Hansen, Steen Holger, 2008, In: Forensic Science International. 177, 2-3, p. 248-251 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytical validation of methods - With statistical methods.
Linnet, Kristian & Boyd, J., 2008, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics.. Burtis, C., Ashwood, ER. & Bruns, D. (eds.). 6 ed. New York: Elsevier, p. 201-228 28 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Chiral analysis of methadone and its main metabolite EDDP in postmortem blood by liquid chromatography-mass spectrometry
Johansen, Sys Stybe & Linnet, Kristian, 2008, In: Journal of Analytical Toxicology. 32, 7, p. 499-504 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dominance of pre-analytical over analytical variation for measurement of methadone and its main metabolite in postmortem femoral blood
Linnet, Kristian, Johansen, Sys Stybe, Buchard, Anders, Munkholm, Julie & Morling, Niels, 2008, In: Forensic Science International. 179, 1, p. 78-82 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
A review on the relation between the brain-serum concentration ratio of drugs and the influence of P-glycoprotein
Ejsing, T. B., Morling, Niels & Linnet, Kristian, 2007, In: Drug Metabolism and Drug Interactions. 22, 2-3, p. 113-29 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Euforiserende stoffer i trafikken
Linnet, Kristian & Steentoft, A., 2007, In: Ugeskrift for læger. 169, 46, p. 3946-3949 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Performance of four mixed-mode solid-phase extraction columns applied to basic drugs in urine
Klinke, H. B. & Linnet, Kristian, 2007, In: Scandinavian Journal of Clinical & Laboratory Investigation. 67, 7, p. 778-782 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions
Hasselstøm, J. & Linnet, Kristian, 6 Jul 2006, In: Drug Metabolism and Drug Interactions. 21, 3-4, p. 187-211 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
[Forensic chemistry: analytical developments and pharmacological aspects].
Linnet, Kristian, Mar 2006, In: Ugeskrift for læger.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytical validation of methods - With statistical methods
Linnet, Kristian, Boyd, J. C., Burtis, C., Ashwood, E. R. & Bruns, D., 2006, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 4 ed. New York: W. B. Saunders Company, p. 353-407 54 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
In vitro studies of quetiapine metabolism using the sunstrate depletion approach with focus on drug-drug interactions
Hasselstrøm, J. & Linnet, Kristian, 2006, In: Drug Metabolism and Drug Interactions. Vol.21, No.3-4, p. 187-211Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Retskemi-Analytiske udviklingstendenser og farmakologiske aspekter
Linnet, Kristian, 2006, In: Ugeskrift for læger. 168/11, p. 1114-16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection and Analytical Evaluations of Methods-With Statistical Techniques
Linnet, Kristian & Boyd, J. C., 2006, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 4.ed. ed. New York, p. 353-407Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
The exponentially weighted moving average (EWMA) rule compared with traditionally used quality control rules
Linnet, Kristian, 2006, In: Clinical Chemistry and Laboratory Medicine. 44, 4, p. 396-399 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of P-glycoprotein on cerebral and hepatic concentrations of nortriptyline and its metabolites
Ejsing, T. B., Hasselstrøm, J. & Linnet, Kristian, 2006, In: Drug Metabolism and Drug Interactions. 21, p. 139-162Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Estimation of the limit of detection with a bootstrap-derived standard error by a partly non-parametric approach. Application to HPLC drug assays
Linnet, Kristian, 2005, In: Clinical Chemistry and Laboratory Medicine. 43, 4, p. 394-399Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of P-glycoprotein inhibition on the distribution of the tricyclic antidepressant nortriptyline over the blood-brain barrier
Ejsing, T. B. & Linnet, Kristian, 2005, In: Human Psychopharmacology. 20, 2, p. 149-153Research output: Contribution to journal › Journal article › Research › peer-review
- Published
P-glycoprotein interaction with risperidone and 9-OH-risperidone studied in vitro, in knock-out mice and in drug-drug interaction experiments
Ejsing, T. B., Pedersen, A. D. & Linnet, Kristian, 2005, In: Human Psychopharmacology 2005. 20, 7, p. 493-500Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
[Comments to the brochure "Genetic tests and drug monitoring" distributed by the Laboratoriet, Epilepsihospitalet in Dianalund].
Linnet, Kristian, Jan 2004, In: Ugeskrift for læger.Research output: Contribution to journal › Journal article › Communication
- Published
A review on the influence of the drug transporter P-glycoprotein on the distribution of drugs over the blood-brain barrier
Linnet, Kristian, 2004, In: Recent Research Developments in Drug Metabolism and Disposition. 2, p. 15-26Research output: Contribution to journal › Review › Research
- Published
An overview on the metabolism of some frequently used antidepressants with focus on involved cytochrome P450 enzymes
Linnet, Kristian, 2004, In: Current Topics in Pharmacology. 8, p. 137-148 12 p.Research output: Contribution to journal › Review › Research
- Published
In vitro microsomal metabolism of imipramine under conditions mimicking the in vivo steady-state situation
Linnet, Kristian, 2004, In: Human Psychopharmacology: Clinical and Experimental. 19, p. 31-36 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kommentarer til brochuren "Genetiske tests og lægemiddelmonitorering uddelt af laboratoriet, Epilepsihospitalet i Dianalund
Linnet, Kristian, 2004, In: Ugeskrift for læger. 166, p. 70-71 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Partly nonparametric approach for determining the limit of detection
Linnet, Kristian & Kondratovich, M., 2004, In: Clinical Chemistry. 50, p. 732-740 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3525
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Chiral Analysis of Methadone and its Main Metabolite, EDDP, in Postmorten Brain and Blood by Automated SPE and Liquid Chromatography-Mass Spectrometry
Research output: Contribution to journal › Journal article › Research › peer-review
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Presence of psychoactive substances in oral fluid from randomly selected drivers in Denmark.
Research output: Contribution to journal › Journal article › Research › peer-review
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Drug-related death in Denmark in 2007
Research output: Contribution to journal › Journal article › Research › peer-review
Published