Temporal Analysis of the Cocaine Metabolite Benzoylecgonine in Wastewater to Estimate Community Drug Use
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Temporal Analysis of the Cocaine Metabolite Benzoylecgonine in Wastewater to Estimate Community Drug Use. / Kinyua, Juliet; Anderson, Todd A.
I: Journal of Forensic Sciences, Bind 57, Nr. 5, 2012, s. 1349-1353.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Temporal Analysis of the Cocaine Metabolite Benzoylecgonine in Wastewater to Estimate Community Drug Use
AU - Kinyua, Juliet
AU - Anderson, Todd A.
PY - 2012
Y1 - 2012
N2 - Indirect estimation methods of cocaine consumption may not reflect the real extent of cocaine use. Another approach is sewage epidemiology. This direct approach is based on analysis of a stable cocaine metabolite, benzoylecgonine (BE), in wastewater. Influent to the Lubbock (Texas) Water Reclamation Plant was sampled twice a week to assess weekly variations in estimates of cocaine consumption over a 5-month period. BE was extracted from influent wastewater samples using solid phase extraction and analyzed using gas chromatography/mass spectrometry. Measured concentrations of BE were converted to cocaine equivalents; the estimated average daily consumption of cocaine during the study period was 1152±147g. Based on BE concentrations and sewage epidemiology, higher cocaine consumption was observed on weekends compared to weekdays (p<0.0003). This method was effective in monitoring BE in wastewater and could be used to complement survey data in estimating cocaine use at a local level.
AB - Indirect estimation methods of cocaine consumption may not reflect the real extent of cocaine use. Another approach is sewage epidemiology. This direct approach is based on analysis of a stable cocaine metabolite, benzoylecgonine (BE), in wastewater. Influent to the Lubbock (Texas) Water Reclamation Plant was sampled twice a week to assess weekly variations in estimates of cocaine consumption over a 5-month period. BE was extracted from influent wastewater samples using solid phase extraction and analyzed using gas chromatography/mass spectrometry. Measured concentrations of BE were converted to cocaine equivalents; the estimated average daily consumption of cocaine during the study period was 1152±147g. Based on BE concentrations and sewage epidemiology, higher cocaine consumption was observed on weekends compared to weekdays (p<0.0003). This method was effective in monitoring BE in wastewater and could be used to complement survey data in estimating cocaine use at a local level.
KW - Benzoylecgonine
KW - Cocaine
KW - Drug use
KW - Forensic science
KW - Gas chromatography/mass spectrometry
KW - Sewage epidemiology
KW - Wastewater
UR - http://www.scopus.com/inward/record.url?scp=84865860556&partnerID=8YFLogxK
U2 - 10.1111/j.1556-4029.2012.02135.x
DO - 10.1111/j.1556-4029.2012.02135.x
M3 - Journal article
C2 - 22509844
AN - SCOPUS:84865860556
VL - 57
SP - 1349
EP - 1353
JO - Journal of Forensic Sciences
JF - Journal of Forensic Sciences
SN - 0022-1198
IS - 5
ER -
ID: 275538562