Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark

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Standard

Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark. / Nielsen, Marie K K; Johansen, Sys Stybe; Linnet, Kristian.

I: Drug and Alcohol Dependence, Bind 133, Nr. 2, 01.12.2013, s. 447-51.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Nielsen, MKK, Johansen, SS & Linnet, K 2013, 'Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark', Drug and Alcohol Dependence, bind 133, nr. 2, s. 447-51. https://doi.org/10.1016/j.drugalcdep.2013.07.001

APA

Nielsen, M. K. K., Johansen, S. S., & Linnet, K. (2013). Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark. Drug and Alcohol Dependence, 133(2), 447-51. https://doi.org/10.1016/j.drugalcdep.2013.07.001

Vancouver

Nielsen MKK, Johansen SS, Linnet K. Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark. Drug and Alcohol Dependence. 2013 dec. 1;133(2):447-51. https://doi.org/10.1016/j.drugalcdep.2013.07.001

Author

Nielsen, Marie K K ; Johansen, Sys Stybe ; Linnet, Kristian. / Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark. I: Drug and Alcohol Dependence. 2013 ; Bind 133, Nr. 2. s. 447-51.

Bibtex

@article{dbb9788237c74637a880fd66da1c3132,

title = "Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark",

abstract = "Methadone blood concentrations in fatal cases are highly variable and there is an appreciable overlap between therapeutic methadone concentrations and the concentrations detected in fatalities. As with other opioids, the background of these methadone-related deaths is unclear. The aim of this study was to investigate if short-time abstinence was contributing to the cause of death in methadone-related deaths by evaluation of the EDDP/methadone ratio in blood and urine.",

author = "Nielsen, {Marie K K} and Johansen, {Sys Stybe} and Kristian Linnet",

year = "2013",

month = dec,

day = "1",

doi = "10.1016/j.drugalcdep.2013.07.001",

language = "English",

volume = "133",

pages = "447--51",

journal = "Drug and Alcohol Dependence",

issn = "0376-8716",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

RIS

TY - JOUR

T1 - Evaluation of metabolite/drug ratios in blood and urine as a tool for confirmation of a reduced tolerance in methadone-related deaths in Denmark

AU - Nielsen, Marie K K

AU - Johansen, Sys Stybe

AU - Linnet, Kristian

PY - 2013/12/1

Y1 - 2013/12/1

N2 - Methadone blood concentrations in fatal cases are highly variable and there is an appreciable overlap between therapeutic methadone concentrations and the concentrations detected in fatalities. As with other opioids, the background of these methadone-related deaths is unclear. The aim of this study was to investigate if short-time abstinence was contributing to the cause of death in methadone-related deaths by evaluation of the EDDP/methadone ratio in blood and urine.

AB - Methadone blood concentrations in fatal cases are highly variable and there is an appreciable overlap between therapeutic methadone concentrations and the concentrations detected in fatalities. As with other opioids, the background of these methadone-related deaths is unclear. The aim of this study was to investigate if short-time abstinence was contributing to the cause of death in methadone-related deaths by evaluation of the EDDP/methadone ratio in blood and urine.

U2 - 10.1016/j.drugalcdep.2013.07.001

DO - 10.1016/j.drugalcdep.2013.07.001

M3 - Journal article

C2 - 23891033

VL - 133

SP - 447

EP - 451

JO - Drug and Alcohol Dependence

JF - Drug and Alcohol Dependence

SN - 0376-8716

IS - 2

ER -

ID: 98315264

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