Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency

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Standard

Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency. / Johansen, S S; Wang, X.; Pedersen, Daniel Sejer; Pearl, P L; Roullet, J-B; Ainslie, G R; Vogel, K R; Gibson, K M.

JIMD Reports. Bind 36 Springer, 2017. s. 93-98 (JIMD Reports).

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt

Harvard

Johansen, SS, Wang, X, Pedersen, DS, Pearl, PL, Roullet, J-B, Ainslie, GR, Vogel, KR & Gibson, KM 2017, Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency. i JIMD Reports. bind 36, Springer, JIMD Reports, s. 93-98. https://doi.org/10.1007/8904_2017_3

APA

Johansen, S. S., Wang, X., Pedersen, D. S., Pearl, P. L., Roullet, J-B., Ainslie, G. R., Vogel, K. R., & Gibson, K. M. (2017). Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency. I JIMD Reports (Bind 36, s. 93-98). Springer. JIMD Reports https://doi.org/10.1007/8904_2017_3

Vancouver

Johansen SS, Wang X, Pedersen DS, Pearl PL, Roullet J-B, Ainslie GR o.a. Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency. I JIMD Reports. Bind 36. Springer. 2017. s. 93-98. (JIMD Reports). https://doi.org/10.1007/8904_2017_3

Author

Johansen, S S ; Wang, X. ; Pedersen, Daniel Sejer ; Pearl, P L ; Roullet, J-B ; Ainslie, G R ; Vogel, K R ; Gibson, K M. / Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency. JIMD Reports. Bind 36 Springer, 2017. s. 93-98 (JIMD Reports).

Bibtex

@inbook{ce5b029b431e4a43afc346bc12dc9ea6,
title = "Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency",
abstract = "Gamma-hydroxybutyrate (GHB) is a drug of abuse, an approved therapeutic for narcolepsy, an agent employed for facilitation of sexual assault, as well as a biomarker of succinic semialdehyde dehydrogenase deficiency (SSADHD). Our laboratory seeks to identify surrogate biomarkers in SSADHD that can shed light on the developmental course of this neurometabolic disease. Since GHB may be quantified in hair as a potential surrogate to identify victims of drug-related assault, we have opted to examine its level in SSADHD. We quantified GHB in hair derived from ten patients with SSADHD, and documented a significant negative age correlation. These findings are consistent with recent results in patient biological fluids, including plasma and red blood cells. These findings may provide additional insight into the developmental course of SSADHD (Jansen et al., J Inherit Metab Dis 39:795-800, 2016).",
author = "Johansen, {S S} and X. Wang and Pedersen, {Daniel Sejer} and Pearl, {P L} and J-B Roullet and Ainslie, {G R} and Vogel, {K R} and Gibson, {K M}",
year = "2017",
doi = "10.1007/8904_2017_3",
language = "English",
isbn = "978-3-662-56137-9",
volume = "36",
series = "JIMD Reports",
publisher = "Springer",
pages = "93--98",
booktitle = "JIMD Reports",
address = "Switzerland",

}

RIS

TY - CHAP

T1 - Gamma-Hydroxybutyrate (GHB) Content in Hair Samples Correlates Negatively with Age in Succinic Semialdehyde Dehydrogenase Deficiency

AU - Johansen, S S

AU - Wang, X.

AU - Pedersen, Daniel Sejer

AU - Pearl, P L

AU - Roullet, J-B

AU - Ainslie, G R

AU - Vogel, K R

AU - Gibson, K M

PY - 2017

Y1 - 2017

N2 - Gamma-hydroxybutyrate (GHB) is a drug of abuse, an approved therapeutic for narcolepsy, an agent employed for facilitation of sexual assault, as well as a biomarker of succinic semialdehyde dehydrogenase deficiency (SSADHD). Our laboratory seeks to identify surrogate biomarkers in SSADHD that can shed light on the developmental course of this neurometabolic disease. Since GHB may be quantified in hair as a potential surrogate to identify victims of drug-related assault, we have opted to examine its level in SSADHD. We quantified GHB in hair derived from ten patients with SSADHD, and documented a significant negative age correlation. These findings are consistent with recent results in patient biological fluids, including plasma and red blood cells. These findings may provide additional insight into the developmental course of SSADHD (Jansen et al., J Inherit Metab Dis 39:795-800, 2016).

AB - Gamma-hydroxybutyrate (GHB) is a drug of abuse, an approved therapeutic for narcolepsy, an agent employed for facilitation of sexual assault, as well as a biomarker of succinic semialdehyde dehydrogenase deficiency (SSADHD). Our laboratory seeks to identify surrogate biomarkers in SSADHD that can shed light on the developmental course of this neurometabolic disease. Since GHB may be quantified in hair as a potential surrogate to identify victims of drug-related assault, we have opted to examine its level in SSADHD. We quantified GHB in hair derived from ten patients with SSADHD, and documented a significant negative age correlation. These findings are consistent with recent results in patient biological fluids, including plasma and red blood cells. These findings may provide additional insight into the developmental course of SSADHD (Jansen et al., J Inherit Metab Dis 39:795-800, 2016).

U2 - 10.1007/8904_2017_3

DO - 10.1007/8904_2017_3

M3 - Book chapter

C2 - 28213850

SN - 978-3-662-56137-9

VL - 36

T3 - JIMD Reports

SP - 93

EP - 98

BT - JIMD Reports

PB - Springer

ER -

ID: 173709501